PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2407888-7 1990 Using scopoletin (40 nM) and 1 microM peroxidase we fluorimetrically measured 1.73 +/- 0.14 and 1.49 +/- 0.19 nmol H2O2/10(6) HMC/hr induced by IL-1 alpha (25 ng/ml) and TNF-alpha (20 ng/ml). Scopoletin 6-16 tumor necrosis factor Homo sapiens 170-179 17113069-4 2007 Scopoletin significantly and dose-dependently inhibits the way in which phorbol 12-myristate 13-acetate (PMA) plus A23187 induces the production of inflammatory cytokines such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, and IL-8 (P<0.05). Scopoletin 0-10 tumor necrosis factor Homo sapiens 179-212 30015831-8 2018 The results demonstrated that scopoletin treatment markedly decreased MMP-1, IL-1alpha and TNFalpha mRNA expression in fibroblasts stimulated with HaCaT conditioned medium (40 mJ/cm2), without any apparent cell cytotoxicity, and in a dose-dependent manner. Scopoletin 30-40 tumor necrosis factor Homo sapiens 91-99 17786283-7 2007 Scopoletin also partially reversed tumor necrosis factor-alpha-induced suppression of LPL activity. Scopoletin 0-10 tumor necrosis factor Homo sapiens 35-62 17113069-5 2007 The maximal rates at which scopoletin (0.2 mM) inhibited the production of TNF-alpha, IL-6, and IL-8 were 41.6%+/-4.2%, 71.9%+/-2.5%, and 43.0%+/-5.7%, respectively. Scopoletin 27-37 tumor necrosis factor Homo sapiens 75-84