PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30930179-6	2019	SKF-38393 administration for 8 weeks induced phosphorylation of sustained ERK1/2 and Bad (Bcl-2-associated death promoter) at Ser155 (BadSer155), and augmented Bax (Bcl-2-associated X protein) expression.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	0-9	mitogen activated protein kinase 3	Rattus norvegicus	74-80	
30930179-9	2019	SKF-38393 (20 and 50 muM) induced sustained ERK1/2 and BadSer155 phosphorylation as well as caspase-3 activation.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	0-9	mitogen activated protein kinase 3	Rattus norvegicus	44-50	
30930179-10	2019	At a non-toxic level (5 muM), SKF-38393 produced only transient ERK1/2 and BadSer112 phosphorylation.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	30-39	mitogen activated protein kinase 3	Rattus norvegicus	64-70	
24672017-7	2014	In one experiment, local infusion of the mGluR5 antagonist MTEP in the DA-denervated rat striatum attenuated the activation of ERK1/2 signaling by SKF38393.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	147-155	mitogen activated protein kinase 3	Rattus norvegicus	127-133	
23328768-6	2013	In these animals, the chronic activation of D1R either by l-DOPA or by the selective D1R agonist SKF 38393 induced both dyskinesia and Shp-2/Erk1/2 activation.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	97-106	mitogen activated protein kinase 3	Rattus norvegicus	141-147	
19647050-4	2009	Our results showed that stimulation of D1 receptor by the specific agonist SKF38393 (10 microM) in PFC and hippocampal slices significantly increased the phosphorylation state of NR1ser897 and NR2Bser1303 subunits of NMDA receptor and of the GLUR1 (ser831 and ser845) subunit of AMPA receptor, as well as of ERK1/2, but not of DARPP-32.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	75-83	mitogen activated protein kinase 3	Rattus norvegicus	308-314	
19647050-5	2009	Interestingly, co-stimulation of D1 and NMDA receptors with an ineffective dose of SKF38393 (2 microM) and NMDA (5 microM) respectively, elevated further the phosphorylation level of NMDA and AMPA receptor subunits, as well as of ERK1/2, but not of DARPP-32.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	83-91	mitogen activated protein kinase 3	Rattus norvegicus	230-236	
34489685-14	2021	The phosphorylation levels of ERK1/2, S6K1, and 4E-BP1 in 6-OHDA-lesioned striatum were increased by L-dopa or D1 receptor agonist SKF38393 (p < 0.05, respectively), not by the combination of L-dopa and D1 receptor antagonist SCH23390, which was similar to the expressions of BMAL1 and CLOCK.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	131-139	mitogen activated protein kinase 3	Rattus norvegicus	30-36	
28583581-7	2017	SKF38393 just significantly improved the gene level of CaMK IV and the protein level of p-CaMK IV (p&lt;0.05) in CSD rats, but it cannot improve the protein expression of ERK1/2 and p-ERK1/2.	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine	0-8	mitogen activated protein kinase 3	Rattus norvegicus	184-190