PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16822944-4	2006	The aim of this study was to determine whether human ASMC (HASMC) express functional IL-8 receptors (CXCR1 and CXCR2) linked to cell contraction and migration.	hasmc	59-64	C-X-C motif chemokine ligand 8	Homo sapiens	85-89	
20875145-10	2010	CONCLUSIONS: We conclude that muscarinic receptors facilitate CSE-induced IL-8 secretion by hASMc via PKC dependent activation of IkappaBalpha and ERK1/2.	hasmc	92-97	C-X-C motif chemokine ligand 8	Homo sapiens	74-78	
16822944-9	2006	IL-8 also contracted the HASMC, decreasing the length of cells by 15%, and induced a 2.5-fold increase in migration.	hasmc	25-30	C-X-C motif chemokine ligand 8	Homo sapiens	0-4	
16029496-11	2005	CONCLUSION: Cigarette smoke may directly cause the release of IL-8 from HASMC, an effect enhanced by TNF-alpha which is overexpressed in COPD.	hasmc	72-77	C-X-C motif chemokine ligand 8	Homo sapiens	62-66	
15982617-13	2005	We also found that p38MAPK, JNK, p42/p44 ERK and NF-kappaB play an important role in IL-17--induced IL-8 production in HASMC in vitro.	hasmc	119-124	C-X-C motif chemokine ligand 8	Homo sapiens	100-104	
12871843-13	2003	Furthermore, GM-CSF, RANTES and to a lesser extent IL-8 release from HASMC treated with TNFalpha and IL-1beta was inhibited dosedependently by SP600125.	hasmc	69-74	C-X-C motif chemokine ligand 8	Homo sapiens	51-55	
12637525-9	2003	Our data demonstrate that the cyclic stretch of HASMC causes the increased production of IL-8 by activating the AP-1 and C/EBP transcription factors through the activation of ERK1/2 and p38 kinase signaling pathways.	hasmc	48-53	C-X-C motif chemokine ligand 8	Homo sapiens	89-93	
14643170-2	2004	This study was performed to investigate the effectiveness of the commonly used steroids beclomethasone, budesonide and fluticasone in downregulating HASMC production of RANTES and IL-8.	hasmc	149-154	C-X-C motif chemokine ligand 8	Homo sapiens	180-184	
26047642-5	2015	Conditioned medium from BK treated HASMC induced CXCL8, VEGF, and COX-2 mRNA and protein accumulation in airway epithelial cells, which were blocked by anti-amphiregulin antibodies and amphiregulin siRNA, suggesting a paracrine effect of HASMC-derived amphiregulin on airway epithelial cells.	hasmc	35-40	C-X-C motif chemokine ligand 8	Homo sapiens	49-54	
26047642-8	2015	Our study provides evidence of a dynamic axis of interaction between HASMC and epithelial cells that amplifies CXCL8, VEGF, COX-2, and amphiregulin production.	hasmc	69-74	C-X-C motif chemokine ligand 8	Homo sapiens	111-116