PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7794810-7	1995	We concluded, therefore, that hemoglobin synthesis in epo-induced J2E cells normally results from the coordinate stimulation of heme and globin synthesis.	Heme	128-132	erythropoietin	Mus musculus	54-57	
15899920-1	2005	The long form of B-cell lymphoma-x (Bcl-x(L)), an outer mitochondrial membrane protein, has been proposed to mediate the antiapoptotic action of erythropoietin on erythroid progenitor cells and to be necessary for heme synthesis in erythroblasts.	Heme	214-218	erythropoietin	Mus musculus	145-159	
3990509-0	1985	Effect of amines on erythropoietin-stimulated heme synthesis in fetal mouse liver cells.	Heme	46-50	erythropoietin	Mus musculus	20-34	
3990509-1	1985	Amines, diamines and polyamines inhibit the erythropoietin-stimulated incorporation of 59Fe into newly-synthesized heme by fetal mouse liver cells in short-term culture.	Heme	115-119	erythropoietin	Mus musculus	44-58	
1168647-10	1975	Despite the different patterns observed for heme synthesis and hemoglobin synthesis, both synthetic activities were consistently higher in cells cultured with erythropoietin as compared to controls.	Heme	44-48	erythropoietin	Mus musculus	159-173	
6831039-4	1983	The addition of EP initiates the final stages of erythroid differentiation, including heme synthesis in 70%-80% of these isolated cells.	Heme	86-90	erythropoietin	Mus musculus	16-18	
647120-1	1978	Erythropoietin (Ep), insulin, and prostaglandins E1 and A1 (PGE1, PGA1) enhanced heme synthesis by mitochondria isolated from embryonic and adult mouse liver cells.	Heme	81-85	erythropoietin	Mus musculus	0-14	
7318980-2	1981	It is a well recognized problem that sample derived transferrin-bound iron (Tf-Fe) interferes with radio-iron incorporation into heme in the in vitro assay of erythropoietin (Ep) using fetal mouse liver cells (FMLC).	Heme	129-133	erythropoietin	Mus musculus	159-173	
678672-3	1978	Investigations on the mouse fetal liver cell bioassay for erythropoietin (ESF) have revealed that iron present in test sera significantly dilutes the radiolabel (59Fe) and thus decreases 59Fe incorporation into heme.	Heme	211-215	erythropoietin	Mus musculus	58-72	
976389-1	1976	It has been shown that erythropoietin-mediated stimulation of heme synthesis in mouse fetal liver cells in vitro is correlated with hydroxyurea sensitivity.	Heme	62-66	erythropoietin	Mus musculus	23-37	
30366982-0	2018	FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.	Heme	60-64	erythropoietin	Mus musculus	14-28