PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24412598-8 2014 In addition, the EX-induced TNF-alpha production observed in response to FG was also attenuated by pretreatment with propranolol. Propranolol 117-128 tumor necrosis factor Mus musculus 28-37 20602110-9 2010 The propranolol treatment completely inhibited exercise-induced TNF-alpha and IFN-alpha suppression in response to R-848 in the mice. Propranolol 4-15 tumor necrosis factor Mus musculus 64-73 22841997-8 2012 In addition to anxiety-like behavior the SDR induced splenomegaly and increase in plasma IL-6, TNFalpha, and MCP-1 were each reversed by pre-treatment with propranolol. Propranolol 156-167 tumor necrosis factor Mus musculus 95-103 20602110-6 2010 In addition, the effect of propranolol (10 mg kg(-1)) as blockade of beta-adrenergic receptors on R-848-induced TNF-alpha and IFN-alpha production in the exercised mice was examined. Propranolol 27-38 tumor necrosis factor Mus musculus 112-121 18421015-5 2008 Propranolol inhalation resulted in enhanced LPS-induced lung inflammation, which was reflected by a stronger secretion of TNF-alpha, IL-6, and monocyte chemoattractant protein-1 into BALF and by enhanced coagulation activation (thrombin-antithrombin complexes). Propranolol 0-11 tumor necrosis factor Mus musculus 122-131 20629735-11 2010 Stress and control + propranolol groups presented a delay in wound contraction, re-epithelialization, F4/80-positive macrophages, neutrophils and mast cells infiltration, cellular proliferation, angiogenesis, myofibroblastic differentiation, MMP-2 and MMP-9 activation and TNF-alpha expression, whereas an increase in the nitrite levels. Propranolol 21-32 tumor necrosis factor Mus musculus 273-282 19060758-0 2009 Propranolol restores the tumor necrosis factor-alpha response of circulating inflammatory monocytes and granulocytes after burn injury and sepsis. Propranolol 0-11 tumor necrosis factor Mus musculus 25-52 19060758-17 2009 Of importance, propranolol treatment partially restored the MFI of ic-TNF (2177 +/- 114) and increased the percentage of inflammatory monocyte subset (F4/80+Gr1+) in BS by 70% compared with saline treatment. Propranolol 15-26 tumor necrosis factor Mus musculus 70-73 16595015-8 2006 In line, inhalation of either salmeterol or salbutamol was associated with a reduced early TNFalpha production in lungs of mice infected intranasally with NTHi, an effect that was reversed by concurrent treatment with the beta blocker propranolol. Propranolol 235-246 tumor necrosis factor Mus musculus 91-99 9119995-5 1997 In contrast, treatment before hemorrhage with the beta-adrenergic receptor antagonist propranolol was associated with increases in mRNA levels for IL-1beta, TNF-alpha, and TGF-beta1, which were greater than those present in untreated hemorrhaged mice, and did not prevent hemorrhage-associated increases in lung IL-1beta protein. Propranolol 86-97 tumor necrosis factor Mus musculus 157-166 10452985-6 1999 When the beta-adrenergic antagonist propranolol was added to the stimulation cultures of l -PAM TuB spleen cells at a concentration that prevented NE-induced cAMP elevation, the NE-mediated decrease in TNF-alpha mRNA and NE-mediated inhibition of CTL generation were reversed. Propranolol 36-47 tumor necrosis factor Mus musculus 202-211 7593548-5 1995 The role of beta-adrenoceptors and endogenous catecholamines is further substantiated by the finding that pretreatment of animals with propranolol alone resulted in a dose-dependent increase of the TNF-alpha response induced by LPS, and that isoproterenol, a non-selective beta-adrenoceptor agonist, decreased it. Propranolol 135-146 tumor necrosis factor Mus musculus 198-207 8730750-5 1996 Systemic production of TNF alpha in response to LPS was increased in adrenalectomized animals and in normal animals treated with the beta-adrenoceptor antagonist, propranolol. Propranolol 163-174 tumor necrosis factor Mus musculus 23-32 6186366-3 1982 The release of TNF was weakly inhibited by the competitive alpha-blocker phentolamine and the beta-blocker propranolol. Propranolol 107-118 tumor necrosis factor Mus musculus 15-18 6186366-11 1982 It is suggested that the inhibition of TNF release by propranolol may be due to the membrane-stabilizing activity of this agent. Propranolol 54-65 tumor necrosis factor Mus musculus 39-42 28539257-8 2017 In addition, beta-blocker propranolol prevented the NF-kB nuclear translocation and the increase in phospho-IkappaB-alpha (Ser32) and in interleukin(IL)-6 expression in aorta of obese mice, without significant changes in either aortic reactive oxygen species production or in circulating IL-6 and TNF-alpha levels. Propranolol 26-37 tumor necrosis factor Mus musculus 297-306 33938511-11 2021 At 24 hours, both propranolol and amitriptyline reduced TNF-alpha levels while allopurinol and ALM reduced TNF-alpha levels only in NN mice. Propranolol 18-29 tumor necrosis factor Mus musculus 56-65 32450072-7 2020 To validate the identified propranolol gene signature obtained in human neutrophils, we analyzed a selection of genes by RT-PCR in mouse EBA skin and confirmed TNF, among others, to be differentially regulated by propranolol treatment. Propranolol 27-38 tumor necrosis factor Mus musculus 160-163 32450072-7 2020 To validate the identified propranolol gene signature obtained in human neutrophils, we analyzed a selection of genes by RT-PCR in mouse EBA skin and confirmed TNF, among others, to be differentially regulated by propranolol treatment. Propranolol 213-224 tumor necrosis factor Mus musculus 160-163 26132918-5 2015 The surgical denervation and beta-adrenergic antagonist propranolol up-regulated TNF-alpha mRNA in both epiWAT and BAT in vivo. Propranolol 56-67 tumor necrosis factor Mus musculus 81-90 25150071-7 2014 Our results showed that the mice immunized with propranolol induced higher levels of antibody, IFN-gamma and TNF-alpha as well as stronger lymphocyte proliferative responses compared with other groups. Propranolol 48-59 tumor necrosis factor Mus musculus 109-118