PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8361879-1	1993	An effect of nonselective beta-adrenergic blockade with propranolol on the blood plasma level of glucagon during insulin-induced hypoglycemia was studies in 20 control dogs and 20 alloxan diabetic dogs.	Propranolol	56-67	insulin	Canis lupus familiaris	113-120	
15898827-8	2004	In a canine model of propranolol intoxication, high-dose insulin provided a sustained increase in systemic blood pressure, cardiac performance and survival rate compared with glucagon or epinephrine.	Propranolol	21-32	insulin	Canis lupus familiaris	57-64	
9458777-6	1998	Phentolamine significantly enhanced, whereas propranolol inhibited, motilin-induced insulin release.	Propranolol	45-56	insulin	Canis lupus familiaris	84-91	
8361879-3	1993	However, glucagon response to insulin-induced hypoglycemia following propranolol administration was increased.	Propranolol	69-80	insulin	Canis lupus familiaris	30-37	
6138714-10	1983	The AUC values for plasma insulin and also for the plasma insulin-glucagon ratio were significantly increased by (--)-propranolol (500 micrograms/kg i.v.)	Propranolol	113-129	insulin	Canis lupus familiaris	26-33	
2857149-7	1985	The fasting-induced decreases in the serum insulin concentration were more pronounced in dogs treated with propranolol.	Propranolol	107-118	insulin	Canis lupus familiaris	43-50	
6138714-10	1983	The AUC values for plasma insulin and also for the plasma insulin-glucagon ratio were significantly increased by (--)-propranolol (500 micrograms/kg i.v.)	Propranolol	113-129	insulin	Canis lupus familiaris	58-65	
6341134-8	1983	Propranolol (0.3 mg/kg, IV) prevented the increase of insulin induced by noradrenaline.	Propranolol	0-11	insulin	Canis lupus familiaris	54-61	
6126351-3	1982	Propranolol, a beta-adrenergic antagonist, significantly decreased portal venous SS and suppressed the isoproterenol-stimulated increases in the levels of SS, insulin, and glucagon.	Propranolol	0-11	insulin	Canis lupus familiaris	159-166	
6123523-8	1982	A pressor response also occurred in propranolol-pretreated dogs during insulin hypoglycemia, but was abolished when the animals also had been pretreated with phentolamine, indicating that the vasoconstrictor action of insulin was mediated via alpha adrenergic receptors.	Propranolol	36-47	insulin	Canis lupus familiaris	71-78	
6123523-11	1982	As propranolol also diminished the inotropic response, it appears that the increase in myocardial blood flow caused by insulin in the normal dog is causally related to the increased myocardial metabolic demand.	Propranolol	3-14	insulin	Canis lupus familiaris	119-126	
206480-6	1978	Propranolol blockade of beta-adrenergic receptors essentially abolishes the insulin response to KCl infusion, with and without epinephrine.	Propranolol	0-11	insulin	Canis lupus familiaris	76-83	
908468-1	1977	Insulin resistance was measured in 16 normal dogs by a method involving the continuous intravenous infusion of epinephrine, propranolol, glucose and insulin.	Propranolol	124-135	insulin	Canis lupus familiaris	0-7	
6288538-4	1982	Insulin treatment, on the other hand, not only improves transfer of a K load, it also alters the response to propranolol.	Propranolol	109-120	insulin	Canis lupus familiaris	0-7	
7024079-3	1981	Treatment with beta receptor blocking dosages of propranolol significantly reduces K transfer capacity, but it also markedly diminishes the KCl stimulated secretory response of insulin, a powerful mediator of K transfer.	Propranolol	49-60	insulin	Canis lupus familiaris	177-184	
6801757-0	1981	The effect of propranolol on insulin-stimulated gastric secretion in dogs.	Propranolol	14-25	insulin	Canis lupus familiaris	29-36	
190857-4	1977	In normal dogs propranolol 0.3 mg/kg intravenously inhibites the insulin release and the hypoglycaemia due to CS 476 suggesting involvement of beta-adrenergic receptors in its action on the pancreas.	Propranolol	15-26	insulin	Canis lupus familiaris	65-72	
1109899-4	1975	Pretreatment with propranolol resulted in a decline of the basal output of both glucagon and insulin and in their marked initial fall at the onset of the stimulus.	Propranolol	18-29	insulin	Canis lupus familiaris	93-100