PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2961012-3	1987	The response to EPI was completely blocked by equimolar propranolol but not by phenoxybenzamine suggesting that, at least in this system, the adrenergic control of ANF secretion is mediated by beta-adrenergic receptors.	Propranolol	56-67	natriuretic peptide A	Rattus norvegicus	164-167	
2526588-12	1989	Phentolamine (1.3 microM) and propranolol (0.1 microM) each reduced peak hypoxia-induced (0% O2) ANF release to 333 and 310%, respectively, whereas atropine sulfate (15 microM) had no inhibitory effect.	Propranolol	30-41	natriuretic peptide A	Rattus norvegicus	97-100	
1980994-9	1990	Conversely, propranolol treatment resulted in lower plasma ANP levels in rats with high sodium intake.	Propranolol	12-23	natriuretic peptide A	Rattus norvegicus	59-62	
1980994-11	1990	The results suggest that dietary sodium intake is an important determinant of the response of atrial-specific granule number and plasma ANP levels following beta-adrenoceptor blockade with propranolol.	Propranolol	189-200	natriuretic peptide A	Rattus norvegicus	136-139	
2932194-8	1985	The relaxant action of synthetic ANF on the renal vessels was seen in the presence of ouabain (1 mM), propranolol (1 microM), phentolamine (1 microM), atropine (1 microM) and felodipine (1 nM).	Propranolol	102-113	natriuretic peptide A	Rattus norvegicus	33-36	
18191303-14	2008	Propranolol and tetrodotoxin significantly (p<0.01) inhibited 55% and 60%, respectively, the toxin-induced ANP release.	Propranolol	0-11	natriuretic peptide A	Rattus norvegicus	110-113	
9365827-6	1997	The ANP-evoked reduction in MAP was not affected in haloperidol- or phentolamine-treated rats (-8.8 +/- 2.3 and -10.5 +/- 2.4%, respectively; both p < 0.005 vs. vehicle) but was abolished in propranolol-treated rats (+3.2 +/- 1.3%; p = ns vs. vehicle).	Propranolol	194-205	natriuretic peptide A	Rattus norvegicus	4-7	
9365827-7	1997	The ANP-induced increase in hematocrit was slightly attenuated in haloperidol-, phentolamine-, and propranolol-treated rats (7.5 +/- 0.7, 7.3 +/- 0.8, and 6.0 +/- 1%, respectively).	Propranolol	99-110	natriuretic peptide A	Rattus norvegicus	4-7	
1531103-10	1992	Propranolol abolished the release of ANP by Iso but not that induced by stretching.	Propranolol	0-11	natriuretic peptide A	Rattus norvegicus	37-40	
7653628-10	1995	Prop partially inhibited the Iso-evoked increases in ANF and FN mRNA, completely prevented the Iso-induced changes in TGF-beta 1 and SERCA mRNA, but had no effect on the Iso-stimulated changes in SK and PNK gene expression.	Propranolol	0-4	natriuretic peptide A	Rattus norvegicus	53-56	
7731062-5	1994	The significant diacylglycerol increase at 10(-10) M ANF, in the presence of propranolol, a potent inhibitor of phosphatidate phosphatase which can hydrolyse phosphatidate to give diacylglycerol, suggested a direct involvement of PC-PLC.	Propranolol	77-88	natriuretic peptide A	Rattus norvegicus	53-56	
8028022-3	1994	Activation of alpha 1-adrenergic receptors by norepinephrine (in the presence of propranolol) increased the rate of ANP secretion approximately two-fold (EC50 = 0.32 microM).	Propranolol	81-92	natriuretic peptide A	Rattus norvegicus	116-119