PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16051698-7 2005 This was sensitive to inhibition by the beta(2)-adrenoceptor antagonists propranolol, timolol, and ICI 118551. Propranolol 73-84 adrenergic receptor, beta 2 Mus musculus 40-60 14744619-4 2004 In mouse ileum, stereoselectivity of propranolol and tertatolol was observed under beta(1)-/beta(2)-adrenoceptor blockade. Propranolol 37-48 adrenergic receptor, beta 2 Mus musculus 92-112 10758054-8 2000 Propranolol administration reduced baseline +dP/dt(max) to nontransgenic levels in all beta(2)AR transgenics except the 350-fold overexpressors, indicating that spontaneous activation of beta(2)AR was present at this level of expression. Propranolol 0-11 adrenergic receptor, beta 2 Mus musculus 87-96 13679574-3 2003 Here we show that beta2AR ligands like ICI118551 and propranolol, which are inverse agonists for Gs-stimulated adenylyl cyclase, induce partial agonist responses for the mitogen-activated protein kinases extracellular signal-regulated kinase (ERK) 1/2 thus behaving as dual efficacy ligands. Propranolol 53-64 adrenergic receptor, beta 2 Mus musculus 18-25 10758054-8 2000 Propranolol administration reduced baseline +dP/dt(max) to nontransgenic levels in all beta(2)AR transgenics except the 350-fold overexpressors, indicating that spontaneous activation of beta(2)AR was present at this level of expression. Propranolol 0-11 adrenergic receptor, beta 2 Mus musculus 187-196 8734469-6 1996 The responses to prenalterol and salbutamol were inhibited by propranolol at relatively low concentrations, suggesting their effects were mediated by beta 1AR and beta 2AR, respectively. Propranolol 62-73 adrenergic receptor, beta 2 Mus musculus 163-171 32450072-1 2020 Propranolol is a ss-adrenoreceptor type 2 (ADRB2) blocker that regulates heart muscle contractions, smooth muscle relaxation and glycogenolysis. Propranolol 0-11 adrenergic receptor, beta 2 Mus musculus 43-48 1438344-7 1992 Additionally, propranolol, a nonspecific beta-blocker, partially reversed the suppression of platelet production by L-thyroxine, lending credence to the assertion that the direct, beta 2-adrenergic receptor-mediated stimulation of the erythroid cell line by thyroxine reported to exist in vitro may also be important in vivo. Propranolol 14-25 adrenergic receptor, beta 2 Mus musculus 180-206 2834198-6 1988 This response was fully blocked by the beta 2AR antagonist, propranolol. Propranolol 60-71 adrenergic receptor, beta 2 Mus musculus 39-47 32138352-3 2020 This study explores the modulation of beta1 and beta2 adrenergic receptors (ADRB1/ADRB2) by propranolol treatment on the peripheral and splenic immune dysfunction of cirrhotic mice. Propranolol 92-103 adrenergic receptor, beta 2 Mus musculus 82-87 32138352-10 2020 In conclusion, suppression of ADRB1 and ADRB2 expressions in spleen and splenic T lymphocytes by acute and chronic propranolol treatment ameliorate systemic and splenic immune dysfunction in cirrhosis. Propranolol 115-126 adrenergic receptor, beta 2 Mus musculus 40-45 30229289-6 2019 The effect of ISO was specifically dependent upon beta2-AR, since it was not seen in adrb2-/- CD8+ T-cells and was blocked by the beta-AR antagonist propranolol. Propranolol 149-160 adrenergic receptor, beta 2 Mus musculus 50-58 30229289-6 2019 The effect of ISO was specifically dependent upon beta2-AR, since it was not seen in adrb2-/- CD8+ T-cells and was blocked by the beta-AR antagonist propranolol. Propranolol 149-160 adrenergic receptor, beta 2 Mus musculus 130-137 25929826-5 2015 Propranolol treatment during PSD reversed these effects, indicating a major inhibitory role of beta-adrenergic receptors (beta-AR) on NK cells function. Propranolol 0-11 adrenergic receptor, beta 2 Mus musculus 122-129 25872592-0 2015 Propranolol represses infantile hemangioma cell growth through the beta2-adrenergic receptor in a HIF-1alpha-dependent manner. Propranolol 0-11 adrenergic receptor, beta 2 Mus musculus 67-92 25872592-5 2015 In vitro analysis revealed that propranolol reduces the expression of HIF-1alpha in hemangioma cells in a dose- and time-dependent manner, mainly by acting on beta2-AR. Propranolol 32-43 adrenergic receptor, beta 2 Mus musculus 159-167 29611347-7 2018 Pretreatment with propranolol, a beta1- and beta2-adrenergic receptor (AR) antagonist, trended toward rescuing the inhibitory effects of NE in primary cell culture. Propranolol 18-29 adrenergic receptor, beta 2 Mus musculus 44-69 29611347-7 2018 Pretreatment with propranolol, a beta1- and beta2-adrenergic receptor (AR) antagonist, trended toward rescuing the inhibitory effects of NE in primary cell culture. Propranolol 18-29 adrenergic receptor, beta 2 Mus musculus 71-73 21177286-4 2011 Stimulation of beta(2)-AR by isoproterenol inhibited Col II mRNA and protein levels by ~50% beginning at 2 h, with both remaining suppressed over 24 h. This inhibition was blocked by propranolol and inhibitors of either MEK1 or PKA. Propranolol 183-194 adrenergic receptor, beta 2 Mus musculus 15-25