PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17166419-1	2006	OBJECTIVE: To explore the effects of Vitamin C (Vit C) on the apoptosis and proliferation inhibition of human peripheral blood mononuclear cells (HPBMCs) induced by deoxynivalenol (DON) in vitro.	deoxynivalenol	165-179	vitrin	Homo sapiens	37-40	
17166419-1	2006	OBJECTIVE: To explore the effects of Vitamin C (Vit C) on the apoptosis and proliferation inhibition of human peripheral blood mononuclear cells (HPBMCs) induced by deoxynivalenol (DON) in vitro.	deoxynivalenol	181-184	vitrin	Homo sapiens	37-40	
17166419-4	2006	Compared with DON group, the apoptosis rate of HPBMCs in 25 micromol/L Vit C pretreatment group was significantly decreased (28.82 +/- 1.67)% vs (22.39 +/- 1.05)%, P < 0.05, while that in 100 micromol/L Vit C pretreatment group was obviously increased (36.07 +/- 2.92)%, P < 0.05.	deoxynivalenol	14-17	vitrin	Homo sapiens	71-74	
17166419-5	2006	Western blotting analysis showed that the expression of Bax and Caspase-3 up-regulated by DON was markedly decreased, while the expression of Bcl-2 down-regulated by DON was increased by 25 micromol/L Vit C pretreatment (P < 0.05).	deoxynivalenol	166-169	vitrin	Homo sapiens	201-204	
17166419-6	2006	100 micromol/L Vit C pretreatment could further increase the expression of Bax and Caspase-3 of HPBMCs induced by DON, while no significant effects on the Bcl-2 expression induced by DON were seen.	deoxynivalenol	114-117	vitrin	Homo sapiens	15-18	
17166419-8	2006	CONCLUSION: 25 micromol/L Vit C pretreatment could at certain extent inhibit the apoptosis and reverse the abnormal expression of apoptosis related genes of HPBMCs induced by DON in vitro, while 100 micromol/L Vit C pretreatment could further increase the apoptosis rate of HPBMCs induced by DON.	deoxynivalenol	175-178	vitrin	Homo sapiens	26-29	
17166419-8	2006	CONCLUSION: 25 micromol/L Vit C pretreatment could at certain extent inhibit the apoptosis and reverse the abnormal expression of apoptosis related genes of HPBMCs induced by DON in vitro, while 100 micromol/L Vit C pretreatment could further increase the apoptosis rate of HPBMCs induced by DON.	deoxynivalenol	292-295	vitrin	Homo sapiens	26-29	
17166419-9	2006	Vit C pretreatment could reverse the proliferation inhibition of HPBMCs induced by DON in vitro.	deoxynivalenol	83-86	vitrin	Homo sapiens	0-3	
17166420-2	2006	METHODS: The effects of Vit C on the changes of HLA-I expression of HPBMCs induced by DON in vitro were evaluated with cell culture, flow cytometry (FCM), Western blotting and immunocytochemical methods.	deoxynivalenol	86-89	vitrin	Homo sapiens	24-27	
17166420-4	2006	As compared with DON group, the HLA-I expressions of HPBMCs in the two Vit C (25 micromol/L and 100 micromol/L) pretreatment groups were all significantly increased (1.15 +/- 0.06 and 1.10 +/- 0.02 vs 0.88 +/- 0.02, P < 0.05).	deoxynivalenol	17-20	vitrin	Homo sapiens	71-74