PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20237592-1	2010	Our previous acute study on urocortin (Ucn) demonstrated that Ucn altered serum and tissue angiotensin-converting enzyme (ACE) activity in rats.	Urocortins	28-37	angiotensin I converting enzyme	Rattus norvegicus	122-125	
16488667-1	2006	We investigated the relationship between urocortin and the activity of angiotensin-converting enzyme (ACE), which plays a key role in producing the potent vasoconstrictor angiotensin II (Ang II).	Urocortins	41-50	angiotensin I converting enzyme	Rattus norvegicus	102-105	
16488667-4	2006	Immunofluorescence studies were also preformed to evaluate the effect of urocortin on ACE in cultured rat aortic endothelial cells (RAECs).	Urocortins	73-82	angiotensin I converting enzyme	Rattus norvegicus	86-89	
16488667-6	2006	The prolonged administration of urocortin enhanced tissue ACE activity but the serum ACE level remained low.	Urocortins	32-41	angiotensin I converting enzyme	Rattus norvegicus	58-61	
16488667-8	2006	Immunofluorescence studies also demonstrated an increase of ACE intensity in RAECs exposed to urocortin for 72 h. Corticotropin-releasing factor (CRF) receptor blocker, astressin, abolished the effects of urocortin.	Urocortins	94-103	angiotensin I converting enzyme	Rattus norvegicus	60-63	
16488667-8	2006	Immunofluorescence studies also demonstrated an increase of ACE intensity in RAECs exposed to urocortin for 72 h. Corticotropin-releasing factor (CRF) receptor blocker, astressin, abolished the effects of urocortin.	Urocortins	205-214	angiotensin I converting enzyme	Rattus norvegicus	60-63	
16488667-9	2006	Extracellular signal-regulated kinase 1/2 (ERK1/2) pathway blocker, PD98059, also markedly inhibited these effects, suggesting urocortin affects the activity of ACE through the ERK1/2 pathway in rats.	Urocortins	127-136	angiotensin I converting enzyme	Rattus norvegicus	161-164	
16488667-11	2006	Thus, the changes of the ACE activity and its production of Ang II may play a role in the vasodilatory property of urocortin.	Urocortins	115-124	angiotensin I converting enzyme	Rattus norvegicus	25-28