PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10818395-5	2000	A local CRF-BP modulates the paracrine effects of CRF and urocortin.	Urocortins	58-67	corticotropin releasing hormone binding protein	Homo sapiens	8-14	
10656997-4	2000	The human CRF-BP ligand was found to: (a) possess a molecular mass of 4707 Daltons, (b) have an N-terminal amino acid sequence (5 residues) identical to rat urocortin, (c) be detected by a specific urocortin radioimmunoassay, (d) have high affinity for both the human and ovine CRF-BPs and (e) be present in many regions of the ovine brain.	Urocortins	157-166	corticotropin releasing hormone binding protein	Homo sapiens	10-16	
10656997-4	2000	The human CRF-BP ligand was found to: (a) possess a molecular mass of 4707 Daltons, (b) have an N-terminal amino acid sequence (5 residues) identical to rat urocortin, (c) be detected by a specific urocortin radioimmunoassay, (d) have high affinity for both the human and ovine CRF-BPs and (e) be present in many regions of the ovine brain.	Urocortins	198-207	corticotropin releasing hormone binding protein	Homo sapiens	10-16	
10656997-9	2000	We conclude that urocortin is the principal ligand for the CRF-BP in ovine brain and we could find no evidence for a centrally located mammalian sauvagine-like peptide.	Urocortins	17-26	corticotropin releasing hormone binding protein	Homo sapiens	59-65	
10448894-6	1999	This slower dissociation indicates that the CRF-BP may be more effective in clearing urocortin than CRF.	Urocortins	85-94	corticotropin releasing hormone binding protein	Homo sapiens	44-50	
9118350-7	1996	These data indicate that CRF receptor antagonists may be useful for the treatment of the disease states where CRF is elevated such as anxiety and depression, anorexia nervosa and stroke and that ligand inhibitors of CRF-BP may be used to elevate brain levels of "free" urocortin and other CRF-related peptides.	Urocortins	269-278	corticotropin releasing hormone binding protein	Homo sapiens	216-222	
8836534-0	1996	Urocortin interaction with corticotropin-releasing factor (CRF) binding protein (CRF-BP): a novel mechanism for elevating "free" CRF levels in human brain.	Urocortins	0-9	corticotropin releasing hormone binding protein	Homo sapiens	27-79	
8836534-0	1996	Urocortin interaction with corticotropin-releasing factor (CRF) binding protein (CRF-BP): a novel mechanism for elevating "free" CRF levels in human brain.	Urocortins	0-9	corticotropin releasing hormone binding protein	Homo sapiens	81-87	
8836534-1	1996	Here we demonstrate that urocortin, a new mammalian member of the corticotropin-releasing factor (CRF) neuropeptide family has high affinity for both the recombinant human CRF binding protein (CRF-BP) and for a membrane-associated form of the protein solubilized from postmortem human cerebrocortical brain tissue.	Urocortins	25-34	corticotropin releasing hormone binding protein	Homo sapiens	172-191	
8836534-1	1996	Here we demonstrate that urocortin, a new mammalian member of the corticotropin-releasing factor (CRF) neuropeptide family has high affinity for both the recombinant human CRF binding protein (CRF-BP) and for a membrane-associated form of the protein solubilized from postmortem human cerebrocortical brain tissue.	Urocortins	25-34	corticotropin releasing hormone binding protein	Homo sapiens	193-199	
8836534-2	1996	The rank order of binding potency for both the human recombinant CRF-BP and for the solubilized human brain CRF-BP is: urotensin > hCRF > urocortin > sauvagine.	Urocortins	144-153	corticotropin releasing hormone binding protein	Homo sapiens	65-71	
8836534-2	1996	The rank order of binding potency for both the human recombinant CRF-BP and for the solubilized human brain CRF-BP is: urotensin > hCRF > urocortin > sauvagine.	Urocortins	144-153	corticotropin releasing hormone binding protein	Homo sapiens	108-114	
8836534-5	1996	Incubation of human brain postmortem tissue extracts with urocortin and urotensin resulted in a dramatic decrease in hCRF/hCRF-BP levels and a concomitant increase in "free" hCRF levels.	Urocortins	58-67	corticotropin releasing hormone binding protein	Homo sapiens	122-129