PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19654292-6 2009 Importantly, HIF-1alpha signaling was impaired with POX expression due to the increased production of alpha-ketoglutarate, a critical substrate for prolyl hydroxylation and degradation of HIF-1alpha. Ketoglutaric Acids 102-121 proline dehydrogenase 1 Homo sapiens 52-55 23861960-11 2013 This supports a deeper link between proteins of the p53-family and metabolic pathways, as PRODH modulates the balance of proline and glutamate levels and those of their derivative alpha-keto-glutarate (alpha-KG) under normal and pathological (tumor) conditions. Ketoglutaric Acids 180-200 proline dehydrogenase 1 Homo sapiens 90-95 23861960-11 2013 This supports a deeper link between proteins of the p53-family and metabolic pathways, as PRODH modulates the balance of proline and glutamate levels and those of their derivative alpha-keto-glutarate (alpha-KG) under normal and pathological (tumor) conditions. Ketoglutaric Acids 202-210 proline dehydrogenase 1 Homo sapiens 90-95