PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11900466-6 2002 Experiments were conducted to test the role of Broad-Complex (BR-C), an essential component in the ecdysone pathway, in let-7 expression. Ecdysone 99-107 let-7 Drosophila melanogaster 120-125 12812783-6 2003 Here, we ask whether the steroid hormone ecdysone induces let-7 or miR-125 expression at the onset of metamorphosis, attempting to link a known temporal regulator in Drosophila with the heterochronic pathway defined in C. elegans. Ecdysone 41-49 let-7 Drosophila melanogaster 58-63 11900466-7 2002 We show that ecdysone and BR-C are required for let-7 expression, indicating that the ecdysone pathway regulates the temporal expression of let-7 in Drosophila. Ecdysone 13-21 let-7 Drosophila melanogaster 48-53 11900466-7 2002 We show that ecdysone and BR-C are required for let-7 expression, indicating that the ecdysone pathway regulates the temporal expression of let-7 in Drosophila. Ecdysone 13-21 let-7 Drosophila melanogaster 140-145 25081570-11 2014 In testes and ovaries, alterations of the ecdysone-induced let-7 result in aberrant gonadal somatic cell behavior and non-cell-autonomous defects in early germline differentiation. Ecdysone 42-50 let-7 Drosophila melanogaster 59-64