PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16243018-1	2005	New research has revealed that the activity of the insulin-signaling pathway in the prothoracic gland of Drosophila modulates ecdysone release and thereby influences both the duration and rate of larval growth.	Ecdysone	126-134	Insulin-like receptor	Drosophila melanogaster	51-58	
16271526-1	2005	In the fruit fly Drosophila melanogaster, the insulin and ecdysone signaling pathways have long been known to regulate growth and developmental timing, respectively.	Ecdysone	58-66	Insulin-like receptor	Drosophila melanogaster	46-53	
22654869-4	2012	Furthermore, they have shown that the insulin/TOR pathway interacts with hormonal systems, like ecdysone and juvenile hormone, to regulate the timing of development and hence the duration of growth.	Ecdysone	96-104	Insulin-like receptor	Drosophila melanogaster	38-45	
10454568-6	1999	(i) Complete Grb10 expression from cDNA with an ecdysone-regulated transient expression system stimulated PDGF-BB-, IGF-I, and insulin- but not epidermal growth factor (EGF)-induced DNA synthesis in an ecdysone dose-responsive fashion.	Ecdysone	48-56	Insulin-like receptor	Drosophila melanogaster	127-134	
29180716-3	2017	Recently, insulin/FOXO signaling has been implicated in the regulation of insect development via the interaction with insect hormones, such as ecdysone and juvenile hormone.	Ecdysone	143-151	Insulin-like receptor	Drosophila melanogaster	10-17	
3130628-7	1988	Analysis of Schneider L3 cells indicates that the addition of the Drosophila hormone ecdysone, which induces differentiation of the cells, causes a small but reproducible increase in the level of the IDE and the insulin-degrading activity.	Ecdysone	85-93	Insulin-like receptor	Drosophila melanogaster	212-219