PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24722212-7 2014 In the steroidogenic prothoracic gland, loss of Ecd or Prp8 prevents splicing of a large intron from CYP307A2/spookier (spok) pre-mRNA, thus eliminating this essential ecdysone-biosynthetic enzyme and blocking the entry to metamorphosis. Ecdysone 168-176 ecdysoneless cell cycle regulator Homo sapiens 48-51 24722212-9 2014 When expressed in the Ecd-deficient prothoracic gland, hEcd re-establishes spok pre-mRNA splicing and protein expression, restoring ecdysone synthesis and normal development. Ecdysone 132-140 ecdysoneless cell cycle regulator Homo sapiens 22-25 24722212-9 2014 When expressed in the Ecd-deficient prothoracic gland, hEcd re-establishes spok pre-mRNA splicing and protein expression, restoring ecdysone synthesis and normal development. Ecdysone 132-140 ecdysoneless cell cycle regulator Homo sapiens 55-59