PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34411436-10	2021	A methyl sulfonyl pharmacophore was added to the structure in order to increase the affinity for the polar side pocket present in the COX-2 enzyme.	methyl sulfonyl	2-17	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	134-139	
33477020-7	2021	RESULTS: The docking results showed that the synthesized compounds were able to form hydrogen bonds with COX-2 involving methyl sulfonyl, spiroisoxazoline, meta-methoxy and fluoro functional groups.	methyl sulfonyl	121-136	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	105-110	
33071054-0	2021	Design, synthesis and biological assessment of new selective COX-2 inhibitors including methyl sulfonyl moiety.	methyl sulfonyl	88-103	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	61-66	
33071054-4	2021	The design, synthesis and biological activity evaluation of novel derivatives bearing thiazolylhydrazine-methyl sulfonyl moiety as selective COX-2 inhibitors were aimed in this paper.	methyl sulfonyl	105-120	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	141-146