PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34506671-4	2022	The oxidative stress parameters of DTIC-res group showed increased levels of malondialdehyde (MDA), thiol and reduced nuclear p53, 8-hydroxy-2"-deoxyguanosine (8-OH-DG), NF-kB and Nrf2.	Dacarbazine	35-39	transformation related protein 53, pseudogene	Mus musculus	126-129	
34506671-5	2022	In presence of metformin in the resistant induction process to DTIC, (MET-DTIC) cells had increased antioxidant thiols, MDA, nuclear p53, 8-OH-DG, Nrf2 and reducing NF-kB, weakening the DTIC-resistant phenotype.	Dacarbazine	63-67	transformation related protein 53, pseudogene	Mus musculus	133-136	
34979447-7	2021	Caffeine potentiated dacarbazine-induced cytotoxic effects by increasing dacarbazine biotransformation, apoptosis, DNA damage, and malondialdehyde levels; also, caffeine reduced Ki67 and ERK1/2 nuclear labeling and increased p53 labeling in B16F10 cells.	Dacarbazine	21-32	transformation related protein 53, pseudogene	Mus musculus	225-228	
30834527-5	2019	We found that cotreatment with dacarbazine and statins significantly inhibited tumor growth and metastasis via suppression of the RhoA/RhoC/LIM domain kinase/serum response factor/c-Fos pathway and enhanced p53, p21, p27, cleaved caspase-3, and cleaved poly(ADP-ribose) polymerase 1 expression in vivo.	Dacarbazine	31-42	transformation related protein 53, pseudogene	Mus musculus	207-210