PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11304687-7 2001 ET-18-OMe inhibited the E-cadherin functions of MCF-7/AZ cells as measured by inhibition of fast and slow aggregation and by the induction of collagen invasion. edelfosine 0-9 cadherin 1 Homo sapiens 24-34 18097585-3 2008 Here, we demonstrated that the ether lipid ET-18-OMe induced the translocation of E-cadherin and episialin to membrane microdomains, enriched in glycosphingolipids, known to be involved in cell-cell adhesion and cell signaling. edelfosine 43-52 cadherin 1 Homo sapiens 82-92 18097585-4 2008 In addition, it was found that E-cadherin and clusters of episialin colocalized and associated with the glycosphingolipid, MSGb5, upon treatment with ET-18-OMe. edelfosine 150-159 cadherin 1 Homo sapiens 31-41 18097585-5 2008 Together, these results suggest that ET-18-OMe inhibits cell-cell adhesion by inducing the translocation of E-cadherin and episialin into MSGb5-enriched membrane microdomains, which leads to clustering and colocalization of the pro-adhesive E-cadherin and the anti-adhesive episialin thereby inhibiting cell-cell adhesion. edelfosine 37-46 cadherin 1 Homo sapiens 108-118 18097585-5 2008 Together, these results suggest that ET-18-OMe inhibits cell-cell adhesion by inducing the translocation of E-cadherin and episialin into MSGb5-enriched membrane microdomains, which leads to clustering and colocalization of the pro-adhesive E-cadherin and the anti-adhesive episialin thereby inhibiting cell-cell adhesion. edelfosine 37-46 cadherin 1 Homo sapiens 241-251 11304687-11 2001 ET-18-OMe induced finger-like extensions with clustering of episialin together with E-cadherin and carcinoembryonic antigen but not with occludin. edelfosine 0-9 cadherin 1 Homo sapiens 84-94 10432010-7 1999 The potential anti-cancer drug 1-O-octadecyl-2-O-methylglycero-3-phosphocholine (ET-18-OMe, 48 h, 25 microg/ml) belonging to the class of alkyllysophospholipids restored the E-cadherin function in the adhesion-deficient MCF-7/6 cells as evidenced by an increased aggregation. edelfosine 81-90 cadherin 1 Homo sapiens 174-184 10432010-9 1999 We conclude that Ca2+-dependent, E-cadherin-specific homotypic adhesion of MCF-7/AZ or MCF-7/6 cells treated with ET-18-OMe was not affected by sialylation of E-cadherin. edelfosine 114-123 cadherin 1 Homo sapiens 33-43