PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26944919-0 2016 Edelfosine Promotes Apoptosis in Androgen-Deprived Prostate Tumors by Increasing ATF3 and Inhibiting Androgen Receptor Activity. edelfosine 0-10 activating transcription factor 3 Homo sapiens 81-85 26944919-5 2016 Furthermore, edelfosine treatment inhibited the expression of androgen receptor (AR) and was associated with an increase in activating transcription factor 3 (ATF3) expression levels, a stress response gene and a negative regulator of AR transactivation. edelfosine 13-23 activating transcription factor 3 Homo sapiens 124-157 26944919-5 2016 Furthermore, edelfosine treatment inhibited the expression of androgen receptor (AR) and was associated with an increase in activating transcription factor 3 (ATF3) expression levels, a stress response gene and a negative regulator of AR transactivation. edelfosine 13-23 activating transcription factor 3 Homo sapiens 159-163 26944919-6 2016 ATF3 binds to AR after edelfosine + AD and represses the transcriptional activation of AR as demonstrated by PSA promoter studies. edelfosine 23-33 activating transcription factor 3 Homo sapiens 0-4 26944919-7 2016 Knockdown of ATF3 using siRNA-ATF3 reversed the inhibition of PSA promoter activity, suggesting that the growth inhibition effect of edelfosine was ATF3 dependent. edelfosine 133-143 activating transcription factor 3 Homo sapiens 13-17 26944919-7 2016 Knockdown of ATF3 using siRNA-ATF3 reversed the inhibition of PSA promoter activity, suggesting that the growth inhibition effect of edelfosine was ATF3 dependent. edelfosine 133-143 activating transcription factor 3 Homo sapiens 30-34 26944919-7 2016 Knockdown of ATF3 using siRNA-ATF3 reversed the inhibition of PSA promoter activity, suggesting that the growth inhibition effect of edelfosine was ATF3 dependent. edelfosine 133-143 activating transcription factor 3 Homo sapiens 30-34