PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10738248-0 2000 Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells. edelfosine 45-57 caspase 3 Homo sapiens 32-41 34885233-6 2021 This correlated with an increase in caspase-3 activity and PARP breakdown, as a major substrate of caspase-3, following PANC-1 CSC treatment with edelfosine. edelfosine 146-156 caspase 3 Homo sapiens 36-45 34885233-6 2021 This correlated with an increase in caspase-3 activity and PARP breakdown, as a major substrate of caspase-3, following PANC-1 CSC treatment with edelfosine. edelfosine 146-156 caspase 3 Homo sapiens 99-108 25749008-4 2015 Combined treatment of U0126 and edelfosine totally inhibited ERK1/2 phosphorylation, and led to RIPK1 and RelA/NF-kappaB degradation, together with a strong activation of caspase-3 and -8. edelfosine 32-42 caspase 3 Homo sapiens 171-187 16540473-4 2006 c-Jun amino-terminal kinase (JNK) and caspase-3 were accordingly activated at earlier times in edelfosine-treated Jurkat cells as compared with drug-treated HeLa cells. edelfosine 95-105 caspase 3 Homo sapiens 38-47