PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12851688-3 2003 The differential sensitivity of cells to edelfosine"s cytostatic and cytotoxic effects has been attributed to edelfosine-induced changes in the activities of many enzymes, including c-Jun NH2-terminal kinase (JNK), extracellular signal-regulated kinases (ERK), p38 kinase, and poly(ADP-ribose) polymerase (PARP). edelfosine 41-51 poly(ADP-ribose) polymerase 1 Homo sapiens 277-304 12851688-3 2003 The differential sensitivity of cells to edelfosine"s cytostatic and cytotoxic effects has been attributed to edelfosine-induced changes in the activities of many enzymes, including c-Jun NH2-terminal kinase (JNK), extracellular signal-regulated kinases (ERK), p38 kinase, and poly(ADP-ribose) polymerase (PARP). edelfosine 110-120 poly(ADP-ribose) polymerase 1 Homo sapiens 277-304 12851688-3 2003 The differential sensitivity of cells to edelfosine"s cytostatic and cytotoxic effects has been attributed to edelfosine-induced changes in the activities of many enzymes, including c-Jun NH2-terminal kinase (JNK), extracellular signal-regulated kinases (ERK), p38 kinase, and poly(ADP-ribose) polymerase (PARP). edelfosine 110-120 poly(ADP-ribose) polymerase 1 Homo sapiens 306-310 12851688-3 2003 The differential sensitivity of cells to edelfosine"s cytostatic and cytotoxic effects has been attributed to edelfosine-induced changes in the activities of many enzymes, including c-Jun NH2-terminal kinase (JNK), extracellular signal-regulated kinases (ERK), p38 kinase, and poly(ADP-ribose) polymerase (PARP). edelfosine 41-51 poly(ADP-ribose) polymerase 1 Homo sapiens 306-310 34885233-6 2021 This correlated with an increase in caspase-3 activity and PARP breakdown, as a major substrate of caspase-3, following PANC-1 CSC treatment with edelfosine. edelfosine 146-156 poly(ADP-ribose) polymerase 1 Homo sapiens 59-63