PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28450285-11	2017	These findings identify two specific sites on vimentin that are phosphorylated by Cd and highlight the functional significance of vimentin phosphorylation in YAP1/Smad3 signaling that mediates Cd-induced peribronchiolar fibrosis and airway remodeling.	Cadmium	193-195	SMAD family member 3	Homo sapiens	163-168	
30804470-6	2019	Cadmium exposure elevated the level of phosphorylated Smad3, and treatment with the ALK4/5 kinase inhibitors, SB431542 or SB505124, suppressed cadmium-induced HK-2 cell death.	Cadmium	0-7	SMAD family member 3	Homo sapiens	54-59	
30804470-6	2019	Cadmium exposure elevated the level of phosphorylated Smad3, and treatment with the ALK4/5 kinase inhibitors, SB431542 or SB505124, suppressed cadmium-induced HK-2 cell death.	Cadmium	143-150	SMAD family member 3	Homo sapiens	54-59	
30804470-7	2019	Cadmium-induced cell death was attenuated by siRNA-mediated ALK4 or Smad3 silencing, or by treatment with SIS3, a selective inhibitor of TGFbeta1-dependent Smad3 phosphorylation.	Cadmium	0-7	SMAD family member 3	Homo sapiens	68-73	
30804470-7	2019	Cadmium-induced cell death was attenuated by siRNA-mediated ALK4 or Smad3 silencing, or by treatment with SIS3, a selective inhibitor of TGFbeta1-dependent Smad3 phosphorylation.	Cadmium	0-7	SMAD family member 3	Homo sapiens	156-161	
34687772-4	2021	Regarding the mechanisms of Cd-induced EMT, we found Smad3 was activated but without upregulation of TGF-beta.	Cadmium	28-30	SMAD family member 3	Homo sapiens	53-58	
33952801-6	2021	Our findings indicated that cadmium induces PAI-1 expression without affecting t-PA expression up to 20 microM, a non-cytotoxic concentration, and PAI-1 induction by cadmium is partly mediated via Smad2 and Smad3.	Cadmium	166-173	SMAD family member 3	Homo sapiens	207-212