PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23992296-0	2013	Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II-mediated BMP4-oxidative stress cascade.	boldine	0-7	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	83-97	
23992296-7	2013	Boldine reversed impaired relaxations induced by high glucose or angiotensin II (Ang II) in non-diabetic mouse aortas while it reduced the overproduction of ROS and increased phosphorylation of eNOS in db/db mouse aortas.	boldine	0-7	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	65-79	
23992296-7	2013	Boldine reversed impaired relaxations induced by high glucose or angiotensin II (Ang II) in non-diabetic mouse aortas while it reduced the overproduction of ROS and increased phosphorylation of eNOS in db/db mouse aortas.	boldine	0-7	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	81-87	
23992296-9	2013	Ang II-stimulated BMP4 expression was inhibited by boldine, tempol, noggin or losartan.	boldine	51-58	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-6	
23992296-11	2013	CONCLUSIONS AND IMPLICATIONS: Boldine reduced oxidative stress and improved endothelium-dependent relaxation in aortas of diabetic mice largely through inhibiting ROS overproduction associated with Ang II-mediated BMP4-dependent mechanisms.	boldine	30-37	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	198-204