PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31905600-5 2019 We investigated the anti-inflammatory properties of epirubicin on the NLRP3 inflammasome and TLR4-mediated inflammation in PMA-primed THP-1 and in primary human peritoneal macrophages (PM). Epirubicin 52-62 NLR family pyrin domain containing 3 Homo sapiens 70-75 31905600-6 2019 Low-dose epirubicin at non-cytotoxic doses downregulated NLRP3 inflammasome components and reduced the release of cleaved caspase-1, bioactive IL-1beta, and TNF-alpha following NLRP3 activation in a dose-dependent fashion. Epirubicin 9-19 NLR family pyrin domain containing 3 Homo sapiens 57-62 31905600-6 2019 Low-dose epirubicin at non-cytotoxic doses downregulated NLRP3 inflammasome components and reduced the release of cleaved caspase-1, bioactive IL-1beta, and TNF-alpha following NLRP3 activation in a dose-dependent fashion. Epirubicin 9-19 NLR family pyrin domain containing 3 Homo sapiens 177-182