PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11222383-1	2001	The activation of caspase-8, a crucial upstream mediator of death receptor signaling, was investigated in epirubicin- and Taxol-induced apoptosis of B-lymphoma cells.	Epirubicin	106-116	caspase 8	Homo sapiens	18-27	
11222383-3	2001	Indeed, active caspase-8 was readily detected after treatment of mature and immature B-lymphoid cells with epirubicin or Taxol.	Epirubicin	107-117	caspase 8	Homo sapiens	15-24	
34658346-3	2021	MTT assay was used to assess the proliferation of BON-ELF4 cells and BON-Vector cells, and the cell apoptosis induced by treatment with epirubicin (0.1 mumol/L for 24 h) was analyzed by detecting the expressions of cleaved caspase-8, caspase-9, and PARP using Western blotting.	Epirubicin	136-146	caspase 8	Homo sapiens	223-232	
24594218-5	2014	RESULTS: HA22T/VGH cells treated with epirubicin increased the production of reactive oxygen species and nitric oxide, the expression of Fas, FasL, and Fas-associated death domain, and the activities of caspase-8 and caspase-3.	Epirubicin	38-48	caspase 8	Homo sapiens	203-212