PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22806583-6 2012 At their upper therapeutic plasma concentrations, several drugs are expected to inhibit by more than 20 % hOCT1 and could thus interfere with the pharmacokinetics of hOCT1-transported drugs in the kidney and liver, namely trimipramine, desipramine and fluoxetine (by about 37 %), levomepromazine and nefazodone (by about 32 %), and clozapine and amitriptyline (by about 22 %). Fluoxetine 252-262 solute carrier family 22 member 1 Homo sapiens 106-111 22806583-6 2012 At their upper therapeutic plasma concentrations, several drugs are expected to inhibit by more than 20 % hOCT1 and could thus interfere with the pharmacokinetics of hOCT1-transported drugs in the kidney and liver, namely trimipramine, desipramine and fluoxetine (by about 37 %), levomepromazine and nefazodone (by about 32 %), and clozapine and amitriptyline (by about 22 %). Fluoxetine 252-262 solute carrier family 22 member 1 Homo sapiens 166-171 34238184-12 2022 RESULTS: The results showed that amantadine (an OCT1/2 inhibitor) and prazosin (an OCT1/3 inhibitor) significantly decreased the cellular accumulation of fluoxetine (P <.001). Fluoxetine 154-164 solute carrier family 22 member 1 Homo sapiens 48-54 34238184-12 2022 RESULTS: The results showed that amantadine (an OCT1/2 inhibitor) and prazosin (an OCT1/3 inhibitor) significantly decreased the cellular accumulation of fluoxetine (P <.001). Fluoxetine 154-164 solute carrier family 22 member 1 Homo sapiens 83-89 30361780-7 2018 All of the six drugs examined, including amitriptyline, fluoxetine, imipramine, irinotecan, ondansetron, and verapamil, were inhibitors of OCT1/2-mediated morphine uptake. Fluoxetine 56-66 solute carrier family 22 member 1 Homo sapiens 139-143