PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15663564-4	2004	OBJECTIVE: We evaluated whether fexofenadine hydrochloride (FEX), the carboxylic acid metabolite of terfenadine with selective H(1)-receptor antagonist activity, could inhibit MMP production from nasal fibroblasts (NFs) in response to TNF-alpha stimulation in vitro.	fexofenadine	32-58	tumor necrosis factor	Homo sapiens	235-244	
25538104-8	2015	Fexofenadine significantly inhibited the upregulated expression of IL-8 in HCT116 and COLO205 cells stimulated with TNF-alpha.	fexofenadine	0-12	tumor necrosis factor	Homo sapiens	116-125	
15663564-4	2004	OBJECTIVE: We evaluated whether fexofenadine hydrochloride (FEX), the carboxylic acid metabolite of terfenadine with selective H(1)-receptor antagonist activity, could inhibit MMP production from nasal fibroblasts (NFs) in response to TNF-alpha stimulation in vitro.	fexofenadine	60-63	tumor necrosis factor	Homo sapiens	235-244	
15663564-12	2004	FEX also inhibited MMP mRNA expression and NF-kappa B activation in PF and MF after TNF-alpha stimulation.	fexofenadine	0-3	tumor necrosis factor	Homo sapiens	84-93	
15180356-7	2004	Fexofenadine significantly inhibited IL6 (p < 0.004) and TNFalpha (p < 0.004) levels in comparison with placebo.	fexofenadine	0-12	tumor necrosis factor	Homo sapiens	60-68	
15180356-9	2004	Fexofenadine reduces TNFalpha and IL6 levels only.	fexofenadine	0-12	tumor necrosis factor	Homo sapiens	21-29