PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25538104-8 2015 Fexofenadine significantly inhibited the upregulated expression of IL-8 in HCT116 and COLO205 cells stimulated with TNF-alpha. fexofenadine 0-12 tumor necrosis factor Homo sapiens 116-125 15663564-4 2004 OBJECTIVE: We evaluated whether fexofenadine hydrochloride (FEX), the carboxylic acid metabolite of terfenadine with selective H(1)-receptor antagonist activity, could inhibit MMP production from nasal fibroblasts (NFs) in response to TNF-alpha stimulation in vitro. fexofenadine 32-58 tumor necrosis factor Homo sapiens 235-244 15663564-4 2004 OBJECTIVE: We evaluated whether fexofenadine hydrochloride (FEX), the carboxylic acid metabolite of terfenadine with selective H(1)-receptor antagonist activity, could inhibit MMP production from nasal fibroblasts (NFs) in response to TNF-alpha stimulation in vitro. fexofenadine 60-63 tumor necrosis factor Homo sapiens 235-244 15663564-12 2004 FEX also inhibited MMP mRNA expression and NF-kappa B activation in PF and MF after TNF-alpha stimulation. fexofenadine 0-3 tumor necrosis factor Homo sapiens 84-93 15180356-7 2004 Fexofenadine significantly inhibited IL6 (p < 0.004) and TNFalpha (p < 0.004) levels in comparison with placebo. fexofenadine 0-12 tumor necrosis factor Homo sapiens 60-68 15180356-9 2004 Fexofenadine reduces TNFalpha and IL6 levels only. fexofenadine 0-12 tumor necrosis factor Homo sapiens 21-29