PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19232844-4	2009	CYP3A4/5 and transporters were assessed using alfentanil and fexofenadine, respectively.	fexofenadine	61-73	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-6	
11240975-7	2001	The amount of azacyclonol, a CYP3A4 mediated metabolite of fexofenadine, eliminated renally increased on average 2-fold after rifampin dosing; however, this pathway accounted for less than 0.5% of the dose.	fexofenadine	59-71	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	29-35	
10496299-12	1999	Troglitazone may enhance the activities of cytochrome P450 (CYP) 3A and/or transporter(s) thereby reducing the plasma concentrations of terfenadine, cyclosporin, atorvastatin and fexofenadine.	fexofenadine	179-191	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	43-67	
21646440-2	2012	The purpose of this study was to determine the influence of Panax ginseng on CYP3A and P-gp function using the probe substrates midazolam and fexofenadine, respectively.	fexofenadine	142-154	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	77-82	
35455642-7	2022	CYP3A and P-gp phenotypic activities were assessed by the metabolic ratio of midazolam and AUC0-6h of fexofenadine, respectively.	fexofenadine	102-114	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-5	
17230498-8	2007	On the other hand, the stereoselective metabolism of fexofenadine using recombinant CYP3A4 was investigated; however, fexofenadine enantiomers were not metabolized by CYP3A4.	fexofenadine	53-65	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	84-90	
17230498-8	2007	On the other hand, the stereoselective metabolism of fexofenadine using recombinant CYP3A4 was investigated; however, fexofenadine enantiomers were not metabolized by CYP3A4.	fexofenadine	118-130	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	84-90	
15601808-6	2005	This investigation tested the hypothesis that alfentanil and fexofenadine could be administered in combination to probe first-pass CYP3A and P-gp activities in humans.	fexofenadine	61-73	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	131-136	
15601808-17	2005	Alfentanil and fexofenadine in combination appear to be a useful probe for evaluating both first-pass CYP3A and P-gp activities in humans.	fexofenadine	15-27	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	102-107