PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18276836-0 2008 Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers. fexofenadine 115-127 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 Mus musculus 22-69 18276836-5 2008 In the present study, the roles of Mrp3 (Abcc3) and Mrp4 (Abcc4) in the hepatobiliary disposition of fexofenadine were examined in knockout mice using in situ liver perfusion. fexofenadine 101-113 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 Mus musculus 35-39 18276836-6 2008 Compared with that in wild-type mice, basolateral excretion of fexofenadine was impaired, resulting in a approximately 50% decrease in perfusate recovery in Abcc3(-/-) mice; in contrast, fexofenadine hepatobiliary disposition was unaltered in Abcc4(-/-) mice. fexofenadine 63-75 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 Mus musculus 157-162