PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30652318-5 2019 In contrast, atorvastatin, bosentan, etoposide, fexofenadine, fluvastatin, glibenclamide and simeprevir were broadly transported by recombinant monkey OATP1B1, OATP1B3 and OATP2B1. fexofenadine 48-60 solute carrier organic anion transporter family member 1B3 Homo sapiens 160-167 29635947-9 2018 Rifampicin significantly increases plasma concentrations of both enantiomers through inhibition of OATP1B3, whereas enantioselectivity of fexofenadine uptake by OATP1B3-expressing cells has not been observed. fexofenadine 138-150 solute carrier organic anion transporter family member 1B3 Homo sapiens 161-168 16455804-6 2006 Inhibition potency of probenecid for the uptake of fexofenadine was compared between hOAT3 and organic anion-transporting peptide 1B3 (hOATP1B3), a transporter responsible for the hepatic uptake of fexofenadine (Drug Metab Dispos 33:1477-1481, 2005). fexofenadine 198-210 solute carrier organic anion transporter family member 1B3 Homo sapiens 135-143 23115085-5 2013 Rifampicin inhibited the uptake of fexofenadine enantiomers by human hepatocytes via organic anion transporter (OAT) OATP1B3 and its basal-to-apical transport in Caco-2 cells, but not OAT3-mediated or multidrug and toxic compound extrusion 1 (MATE1)-mediated transport. fexofenadine 35-47 solute carrier organic anion transporter family member 1B3 Homo sapiens 117-124 18180276-6 2008 Vectorial basal-to-apical transport of FEX was observed in double transfectants expressing OATP1B1/multidrug resistance-associated protein 2 (MRP2) and OATP1B3/MRP2, suggesting that OATP1B1 as well as OATP1B3 is involved in the hepatic uptake of FEX and that MRP2 can recognize FEX as a substrate. fexofenadine 39-42 solute carrier organic anion transporter family member 1B3 Homo sapiens 152-159 18180276-6 2008 Vectorial basal-to-apical transport of FEX was observed in double transfectants expressing OATP1B1/multidrug resistance-associated protein 2 (MRP2) and OATP1B3/MRP2, suggesting that OATP1B1 as well as OATP1B3 is involved in the hepatic uptake of FEX and that MRP2 can recognize FEX as a substrate. fexofenadine 39-42 solute carrier organic anion transporter family member 1B3 Homo sapiens 201-208 18180276-7 2008 The inhibitory effects of compounds on FEX uptake in OATP1B3-expressing HEK293 cells were investigated, and the maximal degree of increase in plasma AUC of FEX by drug interaction in clinical situations was estimated. fexofenadine 39-42 solute carrier organic anion transporter family member 1B3 Homo sapiens 53-60 16014768-12 2005 In conclusion, this is, to our knowledge, the first demonstration that OATP1B3 is thought to be a major transporter involved in hepatic uptake of FEX in humans. fexofenadine 146-149 solute carrier organic anion transporter family member 1B3 Homo sapiens 71-78