PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28188296-1 2017 The aim of this study was to determine the effects of garlic and ginkgo herbal extracts on the pharmacokinetics of the P-glycoprotein (P-gp)/organic anion-transporting polypeptides (Oatps) substrate fexofenadine. fexofenadine 199-211 phosphoglycolate phosphatase Rattus norvegicus 135-139 16850393-6 2006 Fexofenadine is a substrate for Pgp, Oatp1, Oatp2, and Oatp3. fexofenadine 0-12 phosphoglycolate phosphatase Rattus norvegicus 32-35 20869437-10 2010 Inhibition of Pgp by PSC-833 affected fexofenadine absorption only in distal segments resulting in AUC values comparable to the proximal data. fexofenadine 38-50 phosphoglycolate phosphatase Rattus norvegicus 14-17 20869437-12 2010 CONCLUSION: The study demonstrates that Pgp is responsible for a limitation of fexofenadine absorption from distal small intestine. fexofenadine 79-91 phosphoglycolate phosphatase Rattus norvegicus 40-43 16850393-7 2006 BA appears to preferentially inhibit Oatp3 over Pgp in the intestine, leading to the decreased oral absorption of fexofenadine. fexofenadine 114-126 phosphoglycolate phosphatase Rattus norvegicus 48-51 12134950-3 2002 Rhodamine123, fexofenadine and saquinavir were used as P-gp substrates. fexofenadine 14-26 phosphoglycolate phosphatase Rattus norvegicus 55-59 16625658-10 2006 To further study the utility of ABT, the antihistamine fexofenadine (Fex), which is not significantly metabolized and is a substrate for the uptake and efflux transporters, OATP and P-gp, was tested in rat. fexofenadine 55-67 phosphoglycolate phosphatase Rattus norvegicus 182-186 16625658-10 2006 To further study the utility of ABT, the antihistamine fexofenadine (Fex), which is not significantly metabolized and is a substrate for the uptake and efflux transporters, OATP and P-gp, was tested in rat. fexofenadine 69-72 phosphoglycolate phosphatase Rattus norvegicus 182-186