PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30049950-4 2018 This study determined whether oregano essential oil (OEO) exerts an anti-inflammatory effect on lipopolysaccharide (LPS)-treated murine macrophage cells (RAW264.7 cells) in vitro and elucidated the possible underlying molecular mechanisms. oeo 53-56 toll-like receptor 4 Mus musculus 116-119 30049950-5 2018 The results showed that OEO (2.5-10 mug/mL) inhibited the expression and secretion of interleukin-1 beta (IL-1beta), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) in RAW264.7 cells treated with LPS (1 mug/mL). oeo 24-27 toll-like receptor 4 Mus musculus 214-217 30049950-8 2018 The OEO inhibited the LPS-induced elevation of NADPH oxidase and oxidative stress. oeo 4-7 toll-like receptor 4 Mus musculus 22-25 30049950-10 2018 In conclusion, OEO protects against the LPS-induced RAW264.7 cell inflammatory response through the NADPH oxidase/ROS pathway. oeo 15-18 toll-like receptor 4 Mus musculus 40-43