PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2854223-2 1988 Gonadotropin-releasing hormone (GnRH) produces a rapid and concentration-dependent hydrolysis of polyphosphoinositides in rat anterior pituitary cells in culture. Phosphatidylinositol Phosphates 97-118 gonadotropin releasing hormone 1 Rattus norvegicus 0-30 2688858-1 1989 The initial step in the signal transduction of luteinizing hormone-releasing hormone (LHRH) in rat ovarian cells is the hydrolysis of membrane polyphosphoinositides into inositol phosphates and 1,2-diacylglycerol. Phosphatidylinositol Phosphates 143-164 gonadotropin releasing hormone 1 Rattus norvegicus 47-84 2688858-1 1989 The initial step in the signal transduction of luteinizing hormone-releasing hormone (LHRH) in rat ovarian cells is the hydrolysis of membrane polyphosphoinositides into inositol phosphates and 1,2-diacylglycerol. Phosphatidylinositol Phosphates 143-164 gonadotropin releasing hormone 1 Rattus norvegicus 86-90 2688858-4 1989 These results support the concept that stimulation of polyphosphoinositide hydrolysis is intimately involved in the direct action of LHRH at the level of the ovary. Phosphatidylinositol Phosphates 54-74 gonadotropin releasing hormone 1 Rattus norvegicus 133-137 2854223-2 1988 Gonadotropin-releasing hormone (GnRH) produces a rapid and concentration-dependent hydrolysis of polyphosphoinositides in rat anterior pituitary cells in culture. Phosphatidylinositol Phosphates 97-118 gonadotropin releasing hormone 1 Rattus norvegicus 32-36 3009164-1 1986 GnRH provokes a phospholipid response in rat granulosa cells that has been characterized by increased incorporation of radioactive precursors into phosphatidic acid and phosphatidylinositol, and by depletion of 32P-prelabeled polyphosphoinositides. Phosphatidylinositol Phosphates 226-247 gonadotropin releasing hormone 1 Rattus norvegicus 0-4 3121934-9 1987 The data obtained in pituitary cells give evidence that polyphosphoinositide breakdown is potentially an early step in the action of GnRH on gonadotropin secretion by providing diacylglycerol and inositol phosphates. Phosphatidylinositol Phosphates 56-76 gonadotropin releasing hormone 1 Rattus norvegicus 133-137 3121934-13 1987 In addition, these results show that one possible site of interference of progestins with GnRH-induced gonadotropin secretion may involve polyphosphoinositide breakdown. Phosphatidylinositol Phosphates 138-158 gonadotropin releasing hormone 1 Rattus norvegicus 90-94