PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3090472-1 1986 The effect of angiotensin II (AII) on polyphosphoinositide (PPI) turnover at the pituitary was studied. Phosphatidylinositol Phosphates 38-58 angiotensinogen Rattus norvegicus 14-28 2554890-0 1989 Down-regulation of protein kinase C potentiates angiotensin II-stimulated polyphosphoinositide hydrolysis in vascular smooth-muscle cells. Phosphatidylinositol Phosphates 74-94 angiotensinogen Rattus norvegicus 48-62 2822694-1 1987 Angiotensin II stimulates sequential phospholipase C-mediated hydrolysis of initially the polyphosphoinositides and subsequently phosphatidylinositol (PI) in cultured rat aortic smooth muscle cells resulting in biphasic, sustained formation of diacylglycerol (DG). Phosphatidylinositol Phosphates 90-111 angiotensinogen Rattus norvegicus 0-14 3667589-2 1987 In cultured rat aortic smooth muscle cells, the ang II-induced signaling sequence is biphasic with rapid hydrolysis of the polyphosphoinositides producing an early (15 s) diacylglycerol (DG) peak and a transient rise in inositol trisphosphate (IP3) and more delayed phosphatidylinositol (PI) hydrolysis resulting in sustained DG formation (peak at 5 min). Phosphatidylinositol Phosphates 123-144 angiotensinogen Rattus norvegicus 48-54 2826911-10 1987 AII-induced breakdown of phosphatidylinositol bisphosphate (PIP2) and phosphatidylinositol phosphate (PIP) leads to formation of inositol 1,4,5-trisphosphate (IP3) and inositol 1,4-bisphosphate (IP2). Phosphatidylinositol Phosphates 70-100 angiotensinogen Rattus norvegicus 0-3 2826911-10 1987 AII-induced breakdown of phosphatidylinositol bisphosphate (PIP2) and phosphatidylinositol phosphate (PIP) leads to formation of inositol 1,4,5-trisphosphate (IP3) and inositol 1,4-bisphosphate (IP2). Phosphatidylinositol Phosphates 60-63 angiotensinogen Rattus norvegicus 0-3 3025836-9 1986 These data demonstrate that sustained and massive breakdown of PtdIns phosphates begins within seconds during cell activation by angiotensin II. Phosphatidylinositol Phosphates 63-80 angiotensinogen Rattus norvegicus 129-143 2835988-13 1988 It is proposed that protein kinase C activation plays an important role in the molecular mechanism of desensitization of angiotensin II-stimulated polyphosphoinositide metabolism. Phosphatidylinositol Phosphates 147-167 angiotensinogen Rattus norvegicus 121-135 3090472-1 1986 The effect of angiotensin II (AII) on polyphosphoinositide (PPI) turnover at the pituitary was studied. Phosphatidylinositol Phosphates 38-58 angiotensinogen Rattus norvegicus 30-33 3090472-1 1986 The effect of angiotensin II (AII) on polyphosphoinositide (PPI) turnover at the pituitary was studied. Phosphatidylinositol Phosphates 60-63 angiotensinogen Rattus norvegicus 14-28 3090472-1 1986 The effect of angiotensin II (AII) on polyphosphoinositide (PPI) turnover at the pituitary was studied. Phosphatidylinositol Phosphates 60-63 angiotensinogen Rattus norvegicus 30-33 6477952-11 1984 The rapid decrease in phosphatidylinositol 4,5-bisphosphate labeling after angiotensin II suggests that the polyphosphoinositide is degraded after hormone binding to the receptor and that PI labeling is a secondary event. Phosphatidylinositol Phosphates 108-128 angiotensinogen Rattus norvegicus 75-89 2989037-1 1985 We examined the effect of angiotensin II, a calcium-mobilizing hormone on polyphosphoinositide metabolism in isolated rat adrenal glomerulosa cells. Phosphatidylinositol Phosphates 74-94 angiotensinogen Rattus norvegicus 26-40 6317349-0 1984 Rapid effects of angiotensin-II on polyphosphoinositide metabolism in the rat adrenal glomerulosa. Phosphatidylinositol Phosphates 35-55 angiotensinogen Rattus norvegicus 17-31 6255013-0 1980 Potassium and angiotensin II increase the concentrations of phosphatidic acid, phosphatidylinositol, and polyphosphoinositides in rat adrenal capsules in vitro. Phosphatidylinositol Phosphates 105-126 angiotensinogen Rattus norvegicus 14-28 6255013-2 1980 Addition of increasing amounts of K+ and angiotensin II to the incubation media elicited progressive increases in corticosterone production and capsular concentrations of phosphatidic acid, phosphatidyl-inositol, and polyphosphoinositides. Phosphatidylinositol Phosphates 217-238 angiotensinogen Rattus norvegicus 41-55