PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23454896-5 2013 Nelfinavir is the HIV-PI with highest cytotoxic activity against primary myeloma cells and with an IC50 near therapeutic drug blood levels (8-14 muM), irrespective of bortezomib sensitivity. Nelfinavir 0-10 latexin Homo sapiens 145-148 23454896-6 2013 Only nelfinavir inhibited intracellular proteasome activity in situ at drug concentrations <40 muM. Nelfinavir 5-15 latexin Homo sapiens 98-101 21266539-7 2011 Dose responses allowed calculation of IC(50) values; e.g., for nelfinavir, of 3.4 muM (human Ddi1) and 0.44 muM (Leishmania Ddi1). Nelfinavir 63-73 latexin Homo sapiens 82-85