PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26977874-3 2016 (2016) report that nelfinavir suppresses MITF expression induced by MAPK pathway inhibition in melanoma cells and sensitizes melanoma cells with NRAS or BRAF plus NRAS mutations to MEK inhibitors. Nelfinavir 19-29 NRAS proto-oncogene, GTPase Homo sapiens 145-149 26977879-4 2016 Nelfinavir profoundly sensitizes BRAF and NRAS mutant melanoma cells to MAPK-pathway inhibitors. Nelfinavir 0-10 NRAS proto-oncogene, GTPase Homo sapiens 42-46 26977879-5 2016 Moreover, nelfinavir is effective in BRAF and NRAS mutant melanoma cells isolated from patients progressed on MAPK inhibitor (MAPKi) therapy and in BRAF/NRAS/PTEN mutant tumors. Nelfinavir 10-20 NRAS proto-oncogene, GTPase Homo sapiens 46-50 26977879-5 2016 Moreover, nelfinavir is effective in BRAF and NRAS mutant melanoma cells isolated from patients progressed on MAPK inhibitor (MAPKi) therapy and in BRAF/NRAS/PTEN mutant tumors. Nelfinavir 10-20 NRAS proto-oncogene, GTPase Homo sapiens 153-157