PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22161308-1	2012	PURPOSE: To predict and determine whether the protease inhibitors (PIs) nelfinavir, amprenavir, atazanavir, ritonavir, and saquinavir could serve as metabolic inhibitors of the human CES1 (hCES1) using both molecular modeling techniques and in vitro inhibition assays.	Nelfinavir	72-82	carboxylesterase 1	Homo sapiens	183-187	
22161308-4	2012	RESULTS: Pharmacophore and 2D-QSAR modeling predicted that nelfinavir would serve as a potent hCES1 inhibitor.	Nelfinavir	59-69	carboxylesterase 1	Homo sapiens	94-99	
22161308-8	2012	DDIs could occur when nelfinavir is co-administered with drugs metabolized by hCES1.	Nelfinavir	22-32	carboxylesterase 1	Homo sapiens	78-83