PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31059280-7 2019 Treatments of these foam cells with ritonavir, nelfinavir, and saquinavir at least doubled cholestryl ester accumulation ( P=0.02, 0.0009, and 0.02, respectively), whereas RNA silencing of the AR-RGN top key driver, PQBP1 (polyglutamine binding protein 1), significantly curbed cholestryl ester accumulation following treatment with any of these ART drugs by >37% ( P<0.05). Nelfinavir 47-57 polyglutamine binding protein 1 Homo sapiens 216-221 31059280-7 2019 Treatments of these foam cells with ritonavir, nelfinavir, and saquinavir at least doubled cholestryl ester accumulation ( P=0.02, 0.0009, and 0.02, respectively), whereas RNA silencing of the AR-RGN top key driver, PQBP1 (polyglutamine binding protein 1), significantly curbed cholestryl ester accumulation following treatment with any of these ART drugs by >37% ( P<0.05). Nelfinavir 47-57 polyglutamine binding protein 1 Homo sapiens 223-254