PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9660842-4 1998 At supratherapeutic concentrations, nelfinavir competitively inhibited dextromethorphan O-demethylase (CYP2D6), S-mephenytoin 4-hydroxylase (CYP2C19), and phenacetin O-deethylase (CYP1A2) with Ki concentrations of 68, 126, and 190 microM, respectively. Nelfinavir 36-46 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 180-186 21930825-0 2011 Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. Nelfinavir 176-186 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 126-150 21930825-3 2011 Statistically significant induction of CYP1A2 (2.1-, 2.9-, and 2.2-fold), CYP2B6 (1.8-, 2.4-, and 4-fold), and CYP2C9 (1.3-, 1.8-, and 2.6-fold) was observed after NFV, RTV, or RIF treatment, respectively (as expected, CYP2D6 was not induced). Nelfinavir 164-167 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 39-45