PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15289351-0 2004 Up-regulation of Egr1 by 1,25-dihydroxyvitamin D3 contributes to increased expression of p35 activator of cyclin-dependent kinase 5 and consequent onset of the terminal phase of HL60 cell differentiation. Calcitriol 25-49 cyclin dependent kinase 5 Homo sapiens 106-131 15289351-2 2004 We reported recently that cyclin-dependent kinase (Cdk)5 and p35Nck5a (p35) are expressed in human leukemia HL60 cells induced to differentiate to monocytes by an exposure to 1,25-dihydroxyvitamin D(3) (1,25D(3)), form a complex, and this complex has kinase activity (F. Chen and G. P. Studzinski, Blood 2001;97:3763). Calcitriol 175-201 cyclin dependent kinase 5 Homo sapiens 51-56 11389014-2 2001 In addition to neuronal cells, active Cdk5 complexes have been reported in developing tissues, such as the embryonic muscle and ocular lens, and in human leukemia HL60 cells induced to differentiate by an exposure to 1,25-dihydroxyvitamin D(3); however, its activator in these cells has not been demonstrated. Calcitriol 217-243 cyclin dependent kinase 5 Homo sapiens 38-42 10366442-0 1999 Cyclin-dependent kinase 5 activity enhances monocytic phenotype and cell cycle traverse in 1,25-dihydroxyvitamin D3-treated HL60 cells. Calcitriol 91-115 cyclin dependent kinase 5 Homo sapiens 0-25