PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34359242-0	2021	Methionine and Arginine Supply Alters Abundance of Amino Acid, Insulin Signaling, and Glutathione Metabolism-Related Proteins in Bovine Subcutaneous Adipose Explants Challenged with N-Acetyl-d-sphingosine.	Arginine	15-23	insulin	Bos taurus	63-70	
12214985-2	2002	Arginine supplementation alone caused a significant rise of plasma arginine, urea, and insulin concentrations, whereas glucagon concentrations tended to increase, but there were no significant group differences.	Arginine	0-8	insulin	Bos taurus	87-94	
11229429-0	2001	Contrasting effects of L-arginine on insulin-mediated blood flow and glucose disposal in the elderly.	Arginine	23-33	insulin	Bos taurus	37-44	
11229429-3	2001	We tested the hypothesis that L-arginine, the endogenous precursor for NO synthesis, would augment insulin-mediated vasodilation and in so doing increase insulin-mediated glucose uptake (IMGU) in healthy elderly subjects.	Arginine	30-40	insulin	Bos taurus	99-106	
11229429-3	2001	We tested the hypothesis that L-arginine, the endogenous precursor for NO synthesis, would augment insulin-mediated vasodilation and in so doing increase insulin-mediated glucose uptake (IMGU) in healthy elderly subjects.	Arginine	30-40	insulin	Bos taurus	154-161	
9861541-5	1998	The response of insulin after arginine injection was smaller in the hot compared with the thermoneutral environment; however, arginine injection resulted in a significantly higher secretion of glucagon in the hot environment.	Arginine	30-38	insulin	Bos taurus	16-23	
9772350-0	1996	Crystal structure of (L-Arg)-B0 bovine insulin at 0.21 nm resolution.	Arginine	21-27	insulin	Bos taurus	39-46	
9772350-1	1996	The crystal structure of (L-Arg)-B0 bovine insulin has been determined, using data to 0.21 nm and atomic parameters of 2Zn porcine insulin as a starting model, by the difference.	Arginine	25-31	insulin	Bos taurus	43-50	
9772350-1	1996	The crystal structure of (L-Arg)-B0 bovine insulin has been determined, using data to 0.21 nm and atomic parameters of 2Zn porcine insulin as a starting model, by the difference.	Arginine	25-31	insulin	Bos taurus	131-138	
7642961-1	1995	The immunocytochemical application of a monoclonal antibody (MAb) against the Arg-Arg region at the junction of the C-peptide and the insulin beta-chain of the human proinsulin molecule on rat pancreatic tissue resulted in positive immunogold labeling over the insulin- as well as the glucagon-secreting cells.	Arginine	78-81	insulin	Bos taurus	169-176	
7642961-1	1995	The immunocytochemical application of a monoclonal antibody (MAb) against the Arg-Arg region at the junction of the C-peptide and the insulin beta-chain of the human proinsulin molecule on rat pancreatic tissue resulted in positive immunogold labeling over the insulin- as well as the glucagon-secreting cells.	Arginine	82-85	insulin	Bos taurus	134-141	
9734870-9	1998	Peak values of insulin and glucagon following the arginine injection were significantly higher in the hot than in the TN environment.	Arginine	50-58	insulin	Bos taurus	15-22	
7698503-9	1995	Arginine, theophylline, and propionic acid increased insulin secretion from freshly isolated islets at 3.3 and 14 mmol/l glucose, but not at 25 mmol/l glucose.	Arginine	0-8	insulin	Bos taurus	53-60	
1857778-3	1991	The first phase of L-arginine-stimulated insulin release was also potentiated by pancreastatin (6.9 +/- 0.5 ng/5 min in controls, 8.4 +/- 0.6 ng/5 min in pancreastatin group), but not by CGA.	Arginine	19-29	insulin	Bos taurus	41-48	
34359242-1	2021	The objective was to perform a proof-of-principle study to evaluate the effects of methionine (Met) and arginine (Arg) supply on protein abundance of amino acid, insulin signaling, and glutathione metabolism-related proteins in subcutaneous adipose tissue (SAT) explants under ceramide (Ce) challenge.	Arginine	114-117	insulin	Bos taurus	162-169	
35137127-0	2022	Insulin signaling and antioxidant proteins in adipose tissue explants from dairy cows challenged with hydrogen peroxide are altered by supplementation of arginine or arginine plus methionine.	Arginine	154-162	insulin	Bos taurus	0-7	
35137127-0	2022	Insulin signaling and antioxidant proteins in adipose tissue explants from dairy cows challenged with hydrogen peroxide are altered by supplementation of arginine or arginine plus methionine.	Arginine	166-174	insulin	Bos taurus	0-7	
3512287-1	1986	The release of insulin which occurred in response to arginine, in the conscious calf, differed from that which occurs in response to glucose in that it was not significantly affected by either adrenergic or muscarinic blocking agents.	Arginine	53-61	insulin	Bos taurus	15-22	
3286698-1	1988	Holstein cows just past peak lactation were used in a 3 x 3 Latin square design to determine the effects of arginine infusion on concentrations of somatotropin and insulin in plasma, milk production, and milk composition.	Arginine	108-116	insulin	Bos taurus	164-171	
3286698-6	1988	Injection of arginine into the jugular vein increased concentrations of somatotropin and insulin in plasma, but the increase did not persist for more than 30 min.	Arginine	13-21	insulin	Bos taurus	89-96	
3068267-2	1988	Responses of plasma somatotropin and insulin to arginine were measured at 6 and 15 wk postpartum.	Arginine	48-56	insulin	Bos taurus	37-44	
3906217-0	1985	Secretory responses of insulin, glucagon and 11-hydroxycorticosteroids to arginine injection in calves exposed to heat.	Arginine	74-82	insulin	Bos taurus	23-30	
6394628-0	1984	Arginine infusion stimulates prolactin, growth hormone, insulin, and subsequent lactation in pregnant dairy cows.	Arginine	0-8	insulin	Bos taurus	56-63	
6394628-5	1984	The secretory response of prolactin, growth hormone, and insulin to daily arginine infusion during the entire prepartum period was not diminished.	Arginine	74-82	insulin	Bos taurus	57-64	
6394628-7	1984	Therefore, repeated arginine infusion in late-pregnant cows dramatically increased prolactin, growth hormone, and insulin and tended to increase subsequent milk yield.	Arginine	20-28	insulin	Bos taurus	114-121	
6382603-0	1984	The growth of single crystals of (L-arginine)B0 bovine insulin and their preliminary X-ray crystallographic analysis.	Arginine	33-44	insulin	Bos taurus	55-62	
6382603-1	1984	The crystals of (L-Arg)B0 bovine insulin large enough for X-ray structure analysis have been grown by vapour diffusion in a buffer containing citrate, acetone and zinc chloride.	Arginine	16-22	insulin	Bos taurus	33-40	
6371080-8	1984	Present evidence with arginine and other intermediates of the urea cycle suggest that these substances influence glucose metabolism and insulin action.	Arginine	22-30	insulin	Bos taurus	136-143	
383231-3	1979	Incubation of these cells in the presence of the arginine analogue, L-canavanine, resulted in the inhibition of conversion of newly formed proinsulin to insulin and the appearance of a radioactive component of molecular weight 11,000-12,000.	Arginine	49-57	insulin	Bos taurus	139-149	
383231-3	1979	Incubation of these cells in the presence of the arginine analogue, L-canavanine, resulted in the inhibition of conversion of newly formed proinsulin to insulin and the appearance of a radioactive component of molecular weight 11,000-12,000.	Arginine	49-57	insulin	Bos taurus	142-149	
1175610-13	1975	This may be similar to that in des-A21, des-B30-insulin, as both lack the Arg-B22--Asn-A21 carboxylate ion pair.	Arginine	74-77	insulin	Bos taurus	48-55	
29931243-6	2018	The Arg treatment significantly increased the serum insulin concentration at 3 h post-infusion compared with the saline treatment (P < 0.05), and that of LPS and LPS + Arg treatments were in between Arg and LPS treatments.	Arginine	4-7	insulin	Bos taurus	52-59	
33222863-12	2020	The individual AA Leu, Met, Ile, and Arg increased S6K1 phosphorylation in an insulin-dependent manner.	Arginine	37-40	insulin	Bos taurus	78-85	
33222863-13	2020	Similarly, Met and Arg increased 4E-BP1 phosphorylation in an insulin-dependent manner.	Arginine	19-22	insulin	Bos taurus	62-69	
19213874-5	2009	The results demonstrate that insulin-induced hypercontractility after 8 days of tissue culture was fully prevented by combined treatment of BTSM-strips with the laminin competing peptides Tyr-Ile-Gly-Ser-Arg (YIGSR) and Arg-Gly-Asp-Ser (RGDS).	Arginine	204-207	insulin	Bos taurus	29-36	
22848214-0	2012	Inhibitory effects of arginine on the aggregation of bovine insulin.	Arginine	22-30	insulin	Bos taurus	60-67	
22848214-1	2012	Static and dynamic light scattering were used to investigate the effects of L-arginine, commonly used to inhibit protein aggregation, on the initial aggregation kinetics of solutions of bovine insulin in 20% acetic acid and 0.1 M NaCl as a model system for amyloidosis.	Arginine	76-86	insulin	Bos taurus	193-200	
19213874-5	2009	The results demonstrate that insulin-induced hypercontractility after 8 days of tissue culture was fully prevented by combined treatment of BTSM-strips with the laminin competing peptides Tyr-Ile-Gly-Ser-Arg (YIGSR) and Arg-Gly-Asp-Ser (RGDS).	Arginine	220-223	insulin	Bos taurus	29-36	
17283404-0	2007	Insulin and glucagon secretory patterns during propionate and arginine tolerance tests in Japanese black cattle with growth retardation.	Arginine	62-70	insulin	Bos taurus	0-7