PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31088907-1 2019 We discovered that 90.3% of patients with angiomyolipomas, lymphangioleiomyomatosis (LAM), and tuberous sclerosis complex (TSC) carry the arginine variant of codon 72 (R72) of TP53 and that R72 increases the risk for angiomyolipoma. Arginine 138-146 TSC complex subunit 1 Mus musculus 123-126 14718525-0 2004 Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe. Arginine 25-33 TSC complex subunit 1 Mus musculus 0-4 14718525-3 2004 Here we show that S. pombe lacking tsc1+ or tsc2+ have similar phenotypes including decreased arginine uptake, decreased expression of three amino acid permeases, and low intracellular levels of four members of the arginine biosynthesis pathway. Arginine 94-102 TSC complex subunit 1 Mus musculus 35-39 14718525-3 2004 Here we show that S. pombe lacking tsc1+ or tsc2+ have similar phenotypes including decreased arginine uptake, decreased expression of three amino acid permeases, and low intracellular levels of four members of the arginine biosynthesis pathway. Arginine 215-223 TSC complex subunit 1 Mus musculus 35-39 14718525-7 2004 Taken together, these findings support a model in which arginine uptake is regulated through tsc1+, tsc2+, and rhb1+ in S. pombe and also suggest a role for the Tsc1 and Tsc2 proteins in amino acid biosynthesis and sensing. Arginine 56-64 TSC complex subunit 1 Mus musculus 93-97