PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18480736-10	2008	Arginase isoenzymes AI and AII have high substrate specifi city, but the affi nity to L-arginine is higher for isoenzyme AI than AII.	Arginine	86-96	NLR family pyrin domain containing 3	Homo sapiens	27-30	
31190807-0	2019	NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells.	Arginine	30-38	NLR family pyrin domain containing 3	Homo sapiens	0-5	
18480736-10	2008	Arginase isoenzymes AI and AII have high substrate specifi city, but the affi nity to L-arginine is higher for isoenzyme AI than AII.	Arginine	86-96	NLR family pyrin domain containing 3	Homo sapiens	129-132	
33630211-0	2021	Arginine Regulates NLRP3 Inflammasome Activation Through SIRT1 in Vascular Endothelial Cells.	Arginine	0-8	NLR family pyrin domain containing 3	Homo sapiens	19-24	
16935537-3	2007	The elevated arginine levels induce the second arginase (AII) in patient kidney and kidney tissue culture.	Arginine	13-21	NLR family pyrin domain containing 3	Homo sapiens	57-60	
11829529-6	2002	Transfection with pcDNA-AII increased AII expression and activity but had little effect on nitrite production even if no l-arginine was added.	Arginine	121-131	NLR family pyrin domain containing 3	Homo sapiens	18-27	
11829529-6	2002	Transfection with pcDNA-AII increased AII expression and activity but had little effect on nitrite production even if no l-arginine was added.	Arginine	121-131	NLR family pyrin domain containing 3	Homo sapiens	24-27	
35114687-9	2022	Its central sulfonylurea group interacts with the Walker A motif of the NLRP3 nucleotide-binding domain and is sandwiched between two arginines, explaining the specificity of NLRP3 for this chemical entity.	Arginine	134-143	NLR family pyrin domain containing 3	Homo sapiens	72-77	
35114687-9	2022	Its central sulfonylurea group interacts with the Walker A motif of the NLRP3 nucleotide-binding domain and is sandwiched between two arginines, explaining the specificity of NLRP3 for this chemical entity.	Arginine	134-143	NLR family pyrin domain containing 3	Homo sapiens	175-180	
2913054-8	1989	Induction studies in cell lines that similarly express only the AII isozyme indicated that its activity could be enhanced severalfold by exposure to elevated arginine levels.	Arginine	158-166	NLR family pyrin domain containing 3	Homo sapiens	64-67	
3106550-6	1987	BALB/c apoA-II contains one residue each of histidine and arginine, neither of which are found in the human A-II protein.	Arginine	58-66	NLR family pyrin domain containing 3	Homo sapiens	10-14	
33630211-3	2021	In this study, we aimed to confirm the modulatory effect of Arg on NLRP3 inflammasome and the underlying mechanisms in vascular endothelial cells (ECs).	Arginine	60-63	NLR family pyrin domain containing 3	Homo sapiens	67-72	
33630211-4	2021	Arg suppressed NLRP3 inflammasome activation in ECs stimulated with lipopolysaccharide (LPS) and adenosine triphosphate (ATP).	Arginine	0-3	NLR family pyrin domain containing 3	Homo sapiens	15-20	
33630211-6	2021	Importantly, knockdown of SIRT1 abolished the inhibitory potential of Arg on the activation of NLRP3 inflammasome.	Arginine	70-73	NLR family pyrin domain containing 3	Homo sapiens	95-100	
33630211-8	2021	In addition, Arg may regulate NLRP3 inflammasome activation partly through suppression of ROS production.	Arginine	13-16	NLR family pyrin domain containing 3	Homo sapiens	30-35	
33630211-9	2021	In combination, we speculate that Arg exerts an inhibitory effect on the activation of NLRP3 inflammasome in ECs, which may be partly mediated by SIRT1 and ROS.	Arginine	34-37	NLR family pyrin domain containing 3	Homo sapiens	87-92