PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29956478-11	2018	Furthermore, based on reversible inhibition, masitinib and vatalanib were predicted to increase the plasma exposure to sensitive CYP2C8 and CYP3A4 substrates by >=2-fold.	vatalanib	59-68	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	140-146	
29956478-12	2018	In summary, our data identify midostaurin and nintedanib as time-dependent inhibitors of CYP3A4 and detect a risk of drug-drug interactions between vatalanib and CYP2C8 substrates, and between masitinib, midostaurin and vatalanib and CYP3A4 substrates.	vatalanib	148-157	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	234-240