PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26416848-3	2015	Moreover, 2-chloroadenosine inhibited expression of S-phase kinase-associated protein-2 (Skp2; promotes proteolysis of p27(Kip1)) and upregulated levels of p27(Kip1) (cell-cycle regulator that impairs cyclin D function).	2-Chloroadenosine	10-27	S-phase kinase associated protein 2	Homo sapiens	52-87	
26416848-3	2015	Moreover, 2-chloroadenosine inhibited expression of S-phase kinase-associated protein-2 (Skp2; promotes proteolysis of p27(Kip1)) and upregulated levels of p27(Kip1) (cell-cycle regulator that impairs cyclin D function).	2-Chloroadenosine	10-27	S-phase kinase associated protein 2	Homo sapiens	89-93	
26416848-5	2015	Knockdown of A2B receptors prevented the effects of 2-chloroadenosine on ERK1/2, Akt, Skp2, p27(Kip1), cyclin D1, cyclin A, and proliferation.	2-Chloroadenosine	52-69	S-phase kinase associated protein 2	Homo sapiens	86-90	
26416848-6	2015	Likewise, inhibition of adenylyl cyclase and protein kinase A abrogated 2-chloroadenosine"s inhibitory effects on Skp2 and stimulatory effects on p27(Kip1) and rescued HCASMCs from 2-chloroadenosine-mediated inhibition.	2-Chloroadenosine	72-89	S-phase kinase associated protein 2	Homo sapiens	114-118	
31786976-7	2020	Moreover, 2-chloroadenosine inhibited expression of Skp2 (promotes proteolysis of p27Kip1) and upregulated levels of p27Kip1 (negative cell-cycle regulator).	2-Chloroadenosine	10-27	S-phase kinase associated protein 2	Homo sapiens	52-56