PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24105105-2 2014 Our previous study showed the effect of Vit B12 on morphine tolerance. Morphine 51-59 vitrin Mus musculus 40-43 24105105-9 2014 Co-administration of Vit B12 (100-500 microg/kg) and morphine in 3 days reduced the development of tolerance to morphine analgesic effect (8.2+-0.5 and 7.83+-0.5 s. vs. normal saline, 3.57+-0.3 s). Morphine 112-120 vitrin Mus musculus 21-24 24105105-12 2014 It is concluded that co-administration of Vit B12 and morphine could reduce tolerance to analgesic effect of morphine chronic administration and also reduce its withdrawal symptoms. Morphine 109-117 vitrin Mus musculus 42-45 22588629-8 2012 Vit B12 showed a dose related effect in acute anti-nociceptive test and increased the anti-nociceptive effect of morphine in chronic treatment. Morphine 113-121 vitrin Mus musculus 0-3 22588629-9 2012 Vit B12 demonstrated an anti-nociceptive effect in chronic studies as single or continues daily treatment and increased significantly the anti-nociceptive effect of morphine. Morphine 165-173 vitrin Mus musculus 0-3