PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1687528-0 1991 Differences in the bimodal effects of morphine in the vas deferens of two strains of rats. Morphine 38-46 arginine vasopressin Rattus norvegicus 54-57 25276199-10 2014 Morphine-induced MCN inhibition could result in diminished plasma AVP levels and eventually an increase in urine volume of rats. Morphine 0-8 arginine vasopressin Rattus norvegicus 66-69 23252926-1 2012 AIM: The aim of this study was to examine the effects of desmopressin on morphine withdrawal symptoms and vasopressin level in morphine-dependent subjects. Morphine 127-135 arginine vasopressin Rattus norvegicus 106-117 18180322-2 2008 We hypothesized that in the naturally vasopressin-deficient Brattleboro rat, acute and chronic morphine treatment may lead to reduced HPA axis activity. Morphine 95-103 arginine vasopressin Rattus norvegicus 38-49 18180322-4 2008 Single morphine injection induced a biphasic ACTH and corticosterone elevation with smaller increases in vasopressin-deficient rats. Morphine 7-15 arginine vasopressin Rattus norvegicus 105-116 18180322-6 2008 In rats repeatedly treated with morphine plasma, ACTH and corticosterone levels were elevated both 4 and 16 h after the last injection (short and long withdrawal) and the absence of vasopressin attenuated this response. Morphine 32-40 arginine vasopressin Rattus norvegicus 182-193 18180322-7 2008 Our data suggest that vasopressin plays a prominent role in morphine treatment and withdrawal-induced acute hormonal changes, but does not affect development of chronic hyperactivity of the HPA axis. Morphine 60-68 arginine vasopressin Rattus norvegicus 22-33 12431775-2 2002 Here, by means of in situ hybridization, the changes in CRH and vasopressin (AVP) mRNAs have been analysed within the rat hypothalamic paraventricular nucleus (PVN) during morphine dependence and after naloxone-precipitated morphine withdrawal. Morphine 172-180 arginine vasopressin Rattus norvegicus 77-80 9402040-16 1997 The present study shows that, in addition to the modifications in corticosterone secretion and in hypothalamic NA turnover, chronic morphine administration produces a complex response in the CRF and AVP systems. Morphine 132-140 arginine vasopressin Rattus norvegicus 199-202 1545232-7 1992 In rats made morphine tolerant/dependent by intracerebroventricular infusion of morphine for 5 d, oxytocin and vasopressin release in the perfused brain was initially similar to that in control rats, indicating tolerance to any initial morphine effects. Morphine 80-88 arginine vasopressin Rattus norvegicus 111-122 1545232-7 1992 In rats made morphine tolerant/dependent by intracerebroventricular infusion of morphine for 5 d, oxytocin and vasopressin release in the perfused brain was initially similar to that in control rats, indicating tolerance to any initial morphine effects. Morphine 80-88 arginine vasopressin Rattus norvegicus 111-122 12716409-0 2003 Quantitative analysis of corticotropin-releasing factor and arginine vasopressin mRNA in the hypothalamus during chronic morphine treatment in rats: an in situ hybridization study. Morphine 121-129 arginine vasopressin Rattus norvegicus 69-80 12716409-1 2003 The content of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) in the hypothalamic paraventricular nucleus (PVN) increases during chronic morphine treatment. Morphine 158-166 arginine vasopressin Rattus norvegicus 65-76 12716409-1 2003 The content of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) in the hypothalamic paraventricular nucleus (PVN) increases during chronic morphine treatment. Morphine 158-166 arginine vasopressin Rattus norvegicus 78-81 12716409-11 2003 Similarly, there was a decrease in intensity of AVP mRNA expression in the parvocellular and magnocellular neurones of the PVN in the morphine-group injected with saline, suggesting a decreased synthesis of AVP in these neurones. Morphine 134-142 arginine vasopressin Rattus norvegicus 48-51 12716409-11 2003 Similarly, there was a decrease in intensity of AVP mRNA expression in the parvocellular and magnocellular neurones of the PVN in the morphine-group injected with saline, suggesting a decreased synthesis of AVP in these neurones. Morphine 134-142 arginine vasopressin Rattus norvegicus 207-210 12716409-13 2003 In conclusion, present results show that, in addition to modifications in corticosterone secretion and in noradrenaline turnover, chronic morphine administration produces a reduction in the synthesis of CRF and AVP. Morphine 138-146 arginine vasopressin Rattus norvegicus 211-214 12431775-0 2002 Effect of naloxone-precipitated morphine withdrawal on CRH and vasopressin mRNA expression in the rat hypothalamic paraventricular nucleus. Morphine 32-40 arginine vasopressin Rattus norvegicus 63-74 9580616-0 1998 Alterations in corticotropin-releasing factor and vasopressin content in rat brain during morphine withdrawal: correlation with hypothalamic noradrenergic activity and pituitary-adrenal response. Morphine 90-98 arginine vasopressin Rattus norvegicus 50-61 9402040-0 1997 Differential regulation of corticotropin-releasing factor and vasopressin in discrete brain regions after morphine administration: correlations with hypothalamic noradrenergic activity and pituitary-adrenal response. Morphine 106-114 arginine vasopressin Rattus norvegicus 62-73 9402040-2 1997 We evaluated the effects of acute and chronic morphine administration on the content of CRF and AVP in different hypothalamic and extrahypothalamic (bed nucleus of the stria terminalis, BNST) nuclei in rats. Morphine 46-54 arginine vasopressin Rattus norvegicus 96-99 9376748-5 1997 It may thus be supposed that the genetic differences in the level of endogenous vasopressin or the sensitivity of its receptors are related to the resistance to morphine dependence formation. Morphine 161-169 arginine vasopressin Rattus norvegicus 80-91 1780342-0 1991 Effects of acute and chronic morphine on food intake in rats: modulation by oxytocin and vasopressin. Morphine 29-37 arginine vasopressin Rattus norvegicus 89-100 3215278-5 1988 Both, the vasopressin antiserum and the vasopressin antagonist abolished the morning adrenalectomy-induced hypersensitivity to centrally injected morphine and were not effective when administered to rats that had been adrenalectomized in the evening. Morphine 146-154 arginine vasopressin Rattus norvegicus 10-21 1804971-38 1991 In morphine-infused rats, the basal firing rate of nineteen phasically active, putative vasopressin supraoptic neurones was not different in nineteen phasic cells in controls (6.4 +/- 0.7 vs. 4.2 +/- 0.6 Hz). Morphine 3-11 arginine vasopressin Rattus norvegicus 88-99 2187076-0 1990 Regional changes in sympathetic nerve activity and baroreceptor reflex function and arterial plasma levels of catecholamines, renin and vasopressin during naloxone-precipitated morphine withdrawal in rats. Morphine 177-185 arginine vasopressin Rattus norvegicus 136-147 3215278-5 1988 Both, the vasopressin antiserum and the vasopressin antagonist abolished the morning adrenalectomy-induced hypersensitivity to centrally injected morphine and were not effective when administered to rats that had been adrenalectomized in the evening. Morphine 146-154 arginine vasopressin Rattus norvegicus 40-51 3215278-9 1988 We propose that vasopressin is a critical neuropeptide factor involved in the adrenalectomy-induced hypersensitivity to morphine antinociception. Morphine 120-128 arginine vasopressin Rattus norvegicus 16-27 3795975-6 1986 After inhibition of vasopressin secretion by alcohol load as well as in Brattleboro rats, morphine induced antidiuretic response for the higher doses and diuretic effects for the lower doses. Morphine 90-98 arginine vasopressin Rattus norvegicus 20-31 2900890-12 1988 Concentrations in plasma of vasopressin, measured by radioimmunoassay in samples of femoral arterial blood, rose in morphine-treated rats from 7.4 +/- 2.4 to 29.2 +/- 3.7 pg/ml after naloxone, but did not rise significantly in control rats. Morphine 116-124 arginine vasopressin Rattus norvegicus 28-39 2900890-17 1988 The firing activity of five phasic (putative vasopressin) supraoptic neurones in morphine-treated rats was increased for at least 30 min by the injection of naloxone; these increases were the result of a raised intraburst firing rate with no change in burst duration or frequency. Morphine 81-89 arginine vasopressin Rattus norvegicus 45-56 2938937-0 1986 The concentration of arginine vasopressin in pituitary stalk plasma of the rat after adrenalectomy or morphine. Morphine 102-110 arginine vasopressin Rattus norvegicus 30-41 2938937-7 1986 The iv infusion of morphine sulfate (3 mg/kg) dramatically decreased the concentration of AVP in the portal plasma of the rat (501 +/- 101 pg/ml before morphine vs. 185 +/- 50 pg/ml after morphine). Morphine 19-35 arginine vasopressin Rattus norvegicus 90-93 2938937-7 1986 The iv infusion of morphine sulfate (3 mg/kg) dramatically decreased the concentration of AVP in the portal plasma of the rat (501 +/- 101 pg/ml before morphine vs. 185 +/- 50 pg/ml after morphine). Morphine 19-27 arginine vasopressin Rattus norvegicus 90-93 2938937-9 1986 Morphine administration also decreased systemic plasma AVP concentrations in urethane-anesthetized rats (27.1 +/- 6.6 pg/ml in controls vs. 3.3 +/- 1.3 pg/ml in morphine-treated rats). Morphine 0-8 arginine vasopressin Rattus norvegicus 55-58 2828970-1 1986 The actions of three morphine derivatives with short peptide side chains were evaluated upon the contraction of the isolated, electrically stimulated mouse vas deferens preparation and upon displacement of specifically bound 3H-etorphine in rat brain membranes. Morphine 21-29 arginine vasopressin Rattus norvegicus 156-159 6526264-2 1984 Cycloheximide and actinomycin D also inhibit the tolerance to morphine and ethanol in smooth muscle of rat vas deferens. Morphine 62-70 arginine vasopressin Rattus norvegicus 107-110 6716265-13 1984 These findings are consistent with a temporary inhibition of vasopressin release by morphine. Morphine 84-92 arginine vasopressin Rattus norvegicus 61-72 6145163-8 1984 As morphine has a vasopressin releasing and a brain L-asparaginase inhibiting effect the antidiuretic action of morphine was considered to be linked to its inhibitory effect on the brain L-asparaginase. Morphine 3-11 arginine vasopressin Rattus norvegicus 18-29 3976402-3 1985 The vasopressin concentration in the first voided urine after antidiuresis from morphine treated rats was found to be in the same range as the vasopressin concentration in urine from saline treated rats. Morphine 80-88 arginine vasopressin Rattus norvegicus 4-15 6316368-0 1983 Arginine vasopressin enhances retention of morphine tolerance. Morphine 43-51 arginine vasopressin Rattus norvegicus 9-20 6316368-3 1983 Arginine vasopressin, but not ACTH 4-10, prolonged the retention of morphine tolerance when assessed five weeks after the last injection. Morphine 68-76 arginine vasopressin Rattus norvegicus 9-20 6861716-3 1983 In control rats, morphine (50 micrograms) injected into the third ventricle resulted in a rapid increase in plasma vasopressin concentrations at 10 min, followed by a reduction at 20 min. Morphine 17-25 arginine vasopressin Rattus norvegicus 115-126 6861716-4 1983 The circumventricular organ-lesioned rats, however, showed a pronounced fall in vasopressin secretion both at 10 and 20 min after 50 micrograms morphine. Morphine 144-152 arginine vasopressin Rattus norvegicus 80-91 6861716-5 1983 A similar abolition of the morphine-elicited rise in plasma vasopressin could also be achieved by the iv infusion of small doses of dopamine in normal rats. Morphine 27-35 arginine vasopressin Rattus norvegicus 60-71 4674608-0 1972 Morphine-induced changes in the sensitivity of the isolated colon and vas deferens of the rat. Morphine 0-8 arginine vasopressin Rattus norvegicus 70-73 6145163-0 1984 Vasopressin release by D-aspartic acid, morphine and prolyl-leucyl-glycinamide (PLG) in DI Brattleboro rats. Morphine 40-48 arginine vasopressin Rattus norvegicus 0-11 6274671-1 1981 The effect of beta-endorphin and morphine on neuromuscular twitching of the vas deferens was examined in rats of 10-120 days of age. Morphine 33-41 arginine vasopressin Rattus norvegicus 76-79 6262492-5 1981 A consistent dose-related, naloxone-sensitive inhibition of the All-stimulated increase in plasma vasopressin concentration and drinking behavior (frequency) occurred after enkephalins, beta-endorphin or morphine. Morphine 204-212 arginine vasopressin Rattus norvegicus 98-109 7264975-0 1981 The effect of intracerebroventricular injections of morphine on vasopressin release in the rat. Morphine 52-60 arginine vasopressin Rattus norvegicus 64-75 7264975-3 1981 micro-injections of morphine on vasopressin (AVP) release in the urethane-anaesthetized rat. Morphine 20-28 arginine vasopressin Rattus norvegicus 32-43 7264975-17 1981 Both stimulatory and inhibitory effects of morphine on vasopressin release were naloxone reversible and stereospecific. Morphine 43-51 arginine vasopressin Rattus norvegicus 55-66 7264975-28 1981 The results also suggest the possibility that opiate receptors with different affinities for morphine may be responsible for the stimulatory and inhibitory effects of morphine on vasopressin release. Morphine 93-101 arginine vasopressin Rattus norvegicus 179-190 7264975-28 1981 The results also suggest the possibility that opiate receptors with different affinities for morphine may be responsible for the stimulatory and inhibitory effects of morphine on vasopressin release. Morphine 167-175 arginine vasopressin Rattus norvegicus 179-190 6244503-4 1980 A similar inhibition of the stimulus-evoked vasopressin release is caused by morphine and beta-endorphin, and the inhibitory effects of the enkephalin analogue can be reversed by naloxone. Morphine 77-85 arginine vasopressin Rattus norvegicus 44-55 574456-0 1979 Antidiuretic effect of morphine and vasopressin in morphine tolerant and non-tolerant rats, differential effects on urine composition. Morphine 51-59 arginine vasopressin Rattus norvegicus 36-47 1257364-1 1976 Recently it was reported that vasopressin facilitates the development of resistance to the analgestic action of morphine. Morphine 112-120 arginine vasopressin Rattus norvegicus 30-41 6258678-0 1980 Interactions between morphine and the opioid-like peptides in the rat vas deferens. Morphine 21-29 arginine vasopressin Rattus norvegicus 70-73 6258678-1 1980 1 Morphine, methadone, levorphanol, pethidine, etonitazene and related morphine-like alkaloids produced an increase in the electrically-evoked muscular contraction of the rat vas deferens. Morphine 2-10 arginine vasopressin Rattus norvegicus 175-178 6258678-1 1980 1 Morphine, methadone, levorphanol, pethidine, etonitazene and related morphine-like alkaloids produced an increase in the electrically-evoked muscular contraction of the rat vas deferens. Morphine 71-79 arginine vasopressin Rattus norvegicus 175-178 6158098-1 1980 Both natural (-)-morphine and its unnatural enantiomer (+)-morphine exert an excitatory action on electrically stimulated contractions of rat vas deferens. Morphine 13-25 arginine vasopressin Rattus norvegicus 142-145 6158098-1 1980 Both natural (-)-morphine and its unnatural enantiomer (+)-morphine exert an excitatory action on electrically stimulated contractions of rat vas deferens. Morphine 55-67 arginine vasopressin Rattus norvegicus 142-145 6158098-6 1980 The view that the rat vas deferens is devoid of morphine receptors is now seen as arising from a reverse example of morphine"s dual action: the masking of the inhibitory action of morphine by its concomitant and more potent excitatory action. Morphine 116-124 arginine vasopressin Rattus norvegicus 22-25 28287019-0 2017 Effect of prenatal restraint stress and morphine co-administration on plasma vasopressin concentration and anxiety behaviors in adult rat offspring. Morphine 40-48 arginine vasopressin Rattus norvegicus 77-88 28287019-3 2017 The present study aimed to identify effects of prenatal restraint stress and morphine co-administration on plasma vasopressin concentration (PVC) and anxiety behaviors in rats. Morphine 77-85 arginine vasopressin Rattus norvegicus 114-125 28287019-13 2017 These data emphasize the impact of prenatal stress and morphine on fetal neuroendocrine development, with long-term changes in anxiety-like behaviors and vasopressin secretion. Morphine 55-63 arginine vasopressin Rattus norvegicus 154-165 27533886-6 2016 Here, the classical mu-opioid receptor agonist, morphine robustly inhibited the spontaneous firing rate of vasopressin and oxytocin neurons, and this inhibition was attenuated by pretreatment with the NPFFR1 agonist, RFamide-related peptide-3. Morphine 48-56 arginine vasopressin Rattus norvegicus 107-118 27533886-7 2016 In rats infused with morphine for 6 d, vasopressin neurons were unresponsive to morphine, indicating the development of cellular tolerance, but pretreatment with the NPFFR antagonist, GJ14, restored acute morphine inhibition. Morphine 21-29 arginine vasopressin Rattus norvegicus 39-50 27070740-3 2016 Here we compared the effects of repeated daily treatment of rats with morphine or methadone and subsequent naloxone-precipitated withdrawal on the expression of the Per1, Per2, and Avp mRNAs in the suprachiasmatic nucleus and on arylalkylamine N-acetyltransferase activity in the pineal gland. Morphine 70-78 arginine vasopressin Rattus norvegicus 181-184