PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20700770-5 2010 Addition of 25HC3S to primary rat hepatocytes decreased nuclear LXR and SREBP-1 protein levels, down-regulated their target genes, acetyl CoA carboxylase 1 (ACC1), fatty acid synthase (FAS), and SREBP-2 target gene HMG reductase, key enzymes involved in fatty acid and cholesterol biosynthesis. 25-hydroxycholesterol 3-sulfate 12-18 sterol regulatory element binding transcription factor 2 Rattus norvegicus 195-202