PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20700770-6 2010 25HC3S reduced TNFalpha-induced inflammatory response by increasing cytoplasmic IkappaBalpha levels, decreasing NFkappaB nuclear translocation, and consequently repressing expression of NFkappaB-dependent genes, IL-1beta, TNFalpha, and TRAF1. 25-hydroxycholesterol 3-sulfate 0-6 NFKB inhibitor alpha Rattus norvegicus 80-92 20700770-4 2010 The present study shows that 25HC3S and its precursor, 25-hydroxycholesterol (25HC), diametrically regulate lipid metabolism and inflammatory response via LXR/SREBP-1 and IkappaBalpha/NFkappaB signaling in hepatocytes. 25-hydroxycholesterol 3-sulfate 29-35 NFKB inhibitor alpha Rattus norvegicus 171-183