PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17624300-6 2007 Coincidently, 25HC3S inhibited the activation of sterol regulatory element binding proteins (SREBPs), suggesting that inhibition of cholesterol biosynthesis occurred via blocking SREBP-1 activation, and subsequently by inhibiting the expression of HMG CoA reductase. 25-hydroxycholesterol 3-sulfate 14-20 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 248-265